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Angela Martinez-Monleon

Explore the profile of Angela Martinez-Monleon including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 91
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Recent Articles
1.
Martinez-Monleon A, Gaarder J, Djos A, Kogner P, Fransson S
Int J Oncol . 2023 Jan; 62(2). PMID: 36601748
Neuroblastoma (NB) is a childhood malignancy of the sympathetic nervous system. NB is mainly driven by copy number alterations, such as amplification, large deletions of chromosome arm 11q and gain...
2.
Martinez-Monleon A, Kryh Oberg H, Gaarder J, Berbegall A, Javanmardi N, Djos A, et al.
Sci Rep . 2022 Jul; 12(1):12420. PMID: 35859155
In neuroblastoma, MYCN amplification and 11q-deletion are important, although incomplete, markers of high-risk disease. It is therefore relevant to characterize additional alterations that can function as prognostic and/or predictive markers....
3.
Borjesson V, Martinez-Monleon A, Fransson S, Kogner P, Johnsen J, Milosevic J, et al.
BMC Genomics . 2022 Feb; 23(1):149. PMID: 35184734
Background: Transgenic animal models are crucial for the study of gene function and disease, and are widely utilized in basic biological research, agriculture and pharma industries. Since the current methods...
4.
Fransson S, Martinez-Monleon A, Johansson M, Sjoberg R, Bjorklund C, Ljungman G, et al.
Sci Rep . 2021 Jan; 10(1):22432. PMID: 33384420
Neuroblastoma is the most common and deadly childhood tumor. Relapsed or refractory neuroblastoma has a very poor prognosis despite recent treatment advances. To investigate genomic alterations associated with relapse and...
5.
Siaw J, Javanmardi N, Van den Eynden J, Lind D, Fransson S, Martinez-Monleon A, et al.
Cell Rep . 2020 Sep; 32(12):108171. PMID: 32966799
High-risk neuroblastomas typically display an undifferentiated or poorly differentiated morphology. It is therefore vital to understand molecular mechanisms that block the differentiation process. We identify an important role for oncogenic...
6.
Braekeveldt N, von Stedingk K, Fransson S, Martinez-Monleon A, Lindgren D, Axelson H, et al.
Cancer Res . 2018 Aug; 78(20):5958-5969. PMID: 30154149
Patient-derived xenografts (PDX) and the Avatar, a single PDX mirroring an individual patient, are emerging tools in preclinical cancer research. However, the consequences of intratumor heterogeneity for PDX modeling of...
7.
Ingeson-Carlsson C, Martinez-Monleon A, Nilsson M
Exp Cell Res . 2015 Sep; 338(2):127-35. PMID: 26384551
Tumor microenvironment influences targeted drug therapy. In this study we compared drug responses to RAF and MEK inhibitors on tumor cell migration in 2D and 3D culture of BRAF(V600E) mutant...