Angela J Stroope
Overview
Explore the profile of Angela J Stroope including associated specialties, affiliations and a list of published articles.
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7
Citations
389
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Recent Articles
1.
Masyuk T, Lee S, Radtke B, Stroope A, Huang B, Banales J, et al.
Am J Pathol
. 2013 Nov;
184(1):110-21.
PMID: 24211536
Hepatic cystogenesis in polycystic liver diseases is associated with abnormalities of cholangiocyte cilia. Given the crucial association between cilia and centrosomes, we tested the hypothesis that centrosomal defects occur in...
2.
Masyuk T, Radtke B, Stroope A, Banales J, Gradilone S, Huang B, et al.
Hepatology
. 2012 Nov;
58(1):409-21.
PMID: 23172758
Unlabelled: In polycystic liver (PLD) and kidney (PKD) diseases, increased cyclic adenosine monophosphate (cAMP) levels trigger hepatorenal cystogenesis. A reduction of the elevated cAMP by targeting somatostatin receptors (SSTRs) with...
3.
Masyuk T, Radtke B, Stroope A, Banales J, Masyuk A, Gradilone S, et al.
Gastroenterology
. 2011 Dec;
142(3):622-633.e4.
PMID: 22155366
Background & Aims: In polycystic kidney disease and polycystic liver disease (PLD), the normally nonproliferative hepato-renal epithelia acquire a proliferative, cystic phenotype that is linked to overexpression of cell division...
4.
Banales J, Masyuk T, Bogert P, Huang B, Gradilone S, Lee S, et al.
Am J Pathol
. 2008 Nov;
173(6):1637-46.
PMID: 18988797
Polycystic kidney (PCK) rats are a spontaneous model of autosomal recessive polycystic kidney disease that exhibit cholangiocyte-derived liver cysts. We have previously reported that in normal cholangiocytes a subset of...
5.
Masyuk A, Gradilone S, Banales J, Huang B, Masyuk T, Lee S, et al.
Am J Physiol Gastrointest Liver Physiol
. 2008 Aug;
295(4):G725-34.
PMID: 18687752
Cholangiocytes, the epithelial cells lining intrahepatic bile ducts, contain primary cilia, which are mechano- and osmosensory organelles detecting changes in bile flow and osmolality and transducing them into intracellular signals....
6.
Masyuk A, Masyuk T, Splinter P, Huang B, Stroope A, LaRusso N
Gastroenterology
. 2006 Sep;
131(3):911-20.
PMID: 16952559
Background & Aims: Cholangiocytes have primary cilia extending from the apical plasma membrane into the ductal lumen. While the physiologic significance of cholangiocyte cilia is unknown, studies in renal epithelia...
7.
Muff M, Masyuk T, Stroope A, Huang B, Splinter P, Lee S, et al.
Lab Invest
. 2006 Jun;
86(9):940-50.
PMID: 16783394
In the PCK rat, a rodent model of Autosomal Recessive Polycystic Kidney Disease (ARPKD), a spontaneous splicing mutation of Pkhd1 initiates hepatic cyst development. Cystic cholangiocytes possess short and malformed...