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Angela Hu

Explore the profile of Angela Hu including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 290
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Recent Articles
11.
Wen K, Hu A, Ma G, Fang C, Daly M
J Community Support Oncol . 2015 Mar; 12(12):439-445. PMID: 25811036
Background: The existing knowledge on the survivorship experiences of Chinese American breast cancer survivors (CABCS) has arisen largely from aggregated data across multiethnic or multicancer studies that have focused on...
12.
Jung K, Wang H, Teriete P, Yap J, Chen L, Lanning M, et al.
J Med Chem . 2015 Mar; 58(7):3002-24. PMID: 25734936
The rational design of inhibitors of the bHLH-ZIP oncoprotein c-Myc is hampered by a lack of structure in its monomeric state. We describe herein the design of novel, low-molecular-weight, synthetic...
13.
Rogal S, Hu A, Bandi R, Shaikh O
World J Gastroenterol . 2014 Jul; 20(25):8288-91. PMID: 25009405
Spontaneous splenorenal shunts in the absence of cirrhosis have rarely been reported as a cause hyperammonemia with encephalopathy. Several closure techniques of such lesions have been described. Here we report...
14.
Chauhan J, Wang H, Yap J, Sabato P, Hu A, Prochownik E, et al.
ChemMedChem . 2014 Jul; 9(10):2274-2285. PMID: 24976143
c-Myc is a basic helix-loop-helix-leucine zipper (bHLH-ZIP) transcription factor that is responsible for the transcription of a wide range of target genes involved in many cancer-related cellular processes. Over-expression of...
15.
Wang H, Chauhan J, Hu A, Pendleton K, Yap J, Sabato P, et al.
Oncotarget . 2013 Jun; 4(6):936-47. PMID: 23801058
The c-Myc (Myc) oncoprotein is a high-value therapeutic target given that it is deregulated in multiple types of cancer. However, potent small molecule inhibitors of Myc have been difficult to...
16.
Yap J, Wang H, Hu A, Chauhan J, Jung K, Gharavi R, et al.
Bioorg Med Chem Lett . 2012 Nov; 23(1):370-4. PMID: 23177256
A structure-activity relationship (SAR) study of the c-Myc (Myc) inhibitor 10074-G5 (N-([1,1'-biphenyl]-2-yl)-7-nitrobenzo[c][1,2,5]oxadiazol-4-amine, 1) - which targets a hydrophobic domain of the Myc oncoprotein that is flanked by arginine residues -...
17.
Fang M, Siciliano N, Hersperger A, Roscoe F, Hu A, Ma X, et al.
Proc Natl Acad Sci U S A . 2012 Jun; 109(25):9983-8. PMID: 22665800
CD4(+) T cells are generally regarded as helpers and regulators of the immune response. Although cytolytic CD4(+) T cells have been described, whether those generated during the course of a...
18.
Qi X, Hu A, Wang K, Newman F, Crosby M, Hu B, et al.
Int J Radiat Oncol Biol Phys . 2011 Apr; 82(5):1605-11. PMID: 21489710
Purpose: To investigate respiration-induced heart motion for left-sided breast irradiation using a four-dimensional computed tomography (4DCT) technique and to determine novel indications to assess heart motion and identify breast patients...