Angel Treasa Alex
Overview
Explore the profile of Angel Treasa Alex including associated specialties, affiliations and a list of published articles.
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10
Citations
109
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Recent Articles
1.
Raj A, Chandran C S, Dua K, Kamath V, Alex A
Eur J Pharmacol
. 2024 Aug;
981:176914.
PMID: 39154820
Triple-negative breast cancer (TNBC) is an aggressive and heterogeneous cancer that lacks all three molecular markers, Estrogen, Progesterone, and Human Epidermal Growth Factor Receptor 2 (HER2). This unique characteristic of...
2.
Raj A, Dua K, Nair R, Sarath Chandran C, Alex A
Chem Phys Lipids
. 2023 Jun;
255:105315.
PMID: 37356610
Drug delivery through the skin improves solubility, bioavailability, and unwanted systemic side effects of the drug. The selection of a suitable carrier is a challenging process. The conventional lipid vesicles...
3.
Gopalan D, Pandey A, Alex A, Kalthur G, Pandey S, Udupa N, et al.
Nanotechnology
. 2020 Nov;
32(14):142002.
PMID: 33238254
The current review focuses towards the advancements made in the past decade in the field of nanotechnology for the early Alzheimer's disease (AD) diagnosis. This review includes the application of...
4.
Ramachandran A, Das S, Joseph A, Shenoy G, Alex A, Mudgal J
Curr Neuropharmacol
. 2020 Aug;
19(5):679-692.
PMID: 32851951
Alzheimer's disease (AD) is a complex neurodegenerative disease that leads to insidious deterioration of brain functions and is considered the sixth leading cause of death in the world. Alzheimer's patients...
5.
Suthar S, Bansal S, Narkhede N, Guleria M, Alex A, Joseph A
Chem Pharm Bull (Tokyo)
. 2017 Sep;
65(9):833-839.
PMID: 28867710
The enzyme tyrosinase regulates melanogenesis and skin hyperpigmentation by converting L-3,4-dihydroxyphenylalanine (L-DOPA) into dopaquinone, a key step in the melanin biosynthesis. The present work deals with design and synthesis of...
6.
Suthar S, Bansal S, Alam M, Jaiswal V, Tiwari A, Chaudhary A, et al.
Bioorg Med Chem Lett
. 2015 Oct;
25(22):5281-5.
PMID: 26428872
The 3-substituted oxindole derivatives were designed, synthesized, and evaluated for antidepressant activity by employing forced swimming test, tail suspension test, and MAO-A inhibition assay. Results of biological studies revealed that...
7.
Alex A, Joseph A, Shavi G, Rao J, Udupa N
Drug Deliv
. 2014 Dec;
23(7):2144-2153.
PMID: 25544603
Context: The study was aimed to develop a polymeric nanoparticle formulation of anticancer drug carboplatin using biodegradable polymer polycaprolactone (PCL). The formulation is intended for intranasal administration to treat glioma...
8.
Kasinathan N, Jagani H, Alex A, Volety S, Venkata Rao J
Drug Deliv
. 2014 Jan;
22(3):243-57.
PMID: 24471801
Context: Delivery of a drug into the central nervous system (CNS) is considered difficult. Most of the drugs discovered over the past decade are biological, which are high in molecular...
9.
Joseph A, Shah C, Kumar S, Alex A, Maliyakkal N, Moorkoth S, et al.
Acta Pharm
. 2013 Oct;
63(3):397-408.
PMID: 24152899
A series of novel 5-alkyl/aryl thiadiazole substituted thiazolidin-4-ones were synthesized by a two-step process. In the first step, 5-alkyl/aryl substituted 2-aminothiadiazoles were synthesized, which on reaction with substituted aromatic aldehydes...
10.
Suthar S, Jaiswal V, Lohan S, Bansal S, Chaudhary A, Tiwari A, et al.
Eur J Med Chem
. 2013 Apr;
63:589-602.
PMID: 23548704
Nuclear factor-kappaB (NF-κB) has been reported to regulate various genes involved in cancer and inflammation. Accordingly, drugs suppressing or inhibiting NF-κB may possess both anti-inflammatory and anticancer properties. A library...