Angel Santiago
Overview
Explore the profile of Angel Santiago including associated specialties, affiliations and a list of published articles.
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9
Citations
66
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Recent Articles
1.
Moctezuma B, Santiago A, Burguete-Garcia A, Martinez-Barnetche J, Morales-Gomez C, Hernandez-Chavez C, et al.
Int J Dev Neurosci
. 2024 Mar;
84(7):638-650.
PMID: 38530142
Numerous studies have established associations between single nucleotide polymorphisms (SNPs) and various behavioral and neurodevelopmental conditions. This study explores the links between SNPs in candidate genes involved in central nervous...
2.
Santiago A, Guzman-Ocampo D, Aguayo-Ortiz R, Dominguez L
ACS Chem Neurosci
. 2021 Jul;
12(15):2765-2775.
PMID: 34291906
γ-Secretase (GS) is one of the most attractive molecular targets for the treatment of Alzheimer's disease (AD). Its key role in the final step of amyloid-β peptides generation and its...
3.
Santiago A, Razo-Hernandez R, Pastor N
J Chem Inf Model
. 2020 Jan;
60(2):866-879.
PMID: 31917925
The TATA-box binding protein (TBP) is an important element of the transcription machinery in archaea and eukaryotic organisms. TBP is expressed in organisms adapted to different temperatures, indicating a robust...
4.
Santiago A, Razo-Hernandez R, Pastor N
Chem Biol Drug Des
. 2019 Oct;
95(1):130-149.
PMID: 31569300
The TATA-binding protein (TBP) is a central transcription factor in eukaryotes that interacts with a large number of different transcription factors; thus, affecting these interactions will be lethal for any...
5.
Cristobal-Mondragon G, Lara-Chacon B, Santiago A, De-la-Rosa V, Gonzalez-Gonzalez R, Muniz-Luna J, et al.
FEBS J
. 2019 Jul;
286(23):4797-4818.
PMID: 31298811
GPN-loop GTPases 1 and 3 are required for RNA polymerase II (RNAPII) nuclear import. Gpn1 and Gpn3 display some sequence similarity, physically associate, and their protein expression levels are mutually...
6.
Tejera B, Lopez R, Hidalgo P, Cardenas R, Ballesteros G, Rivillas L, et al.
PLoS One
. 2019 Apr;
14(4):e0214882.
PMID: 30943256
The E1B 55kDa produced by human adenovirus type 5 is a multifunctional protein that participates in the regulation of several steps during the viral replication cycle. Previous studies suggest this...
7.
Rodriguez-Lozada J, Tovar-Gudino E, Guevara-Salazar J, Razo-Hernandez R, Santiago A, Pastor N, et al.
Molecules
. 2018 Nov;
23(11).
PMID: 30445747
We have previously reported the synthesis, in vitro and in silico activities of new GABA analogues as inhibitors of the GABA-AT enzyme from , where the nitrogen atom at the...
8.
Tovar-Gudino E, Guevara-Salazar J, Bahena-Herrera J, Trujillo-Ferrara J, Martinez-Campos Z, Razo-Hernandez R, et al.
Molecules
. 2018 May;
23(5).
PMID: 29747438
γ-Aminobutyric acid (GABA) is the most important inhibitory neurotransmitter in the central nervous system, and a deficiency of GABA is associated with serious neurological disorders. Due to its low lipophilicity,...
9.
Li Y, Wang M, Li H, King K, Bassi R, Sun H, et al.
J Exp Med
. 2002 Jun;
195(12):1575-84.
PMID: 12070285
The vascular endothelial growth factor (VEGF) receptor fetal liver kinase 1 (flk1; VEGFR-2, KDR) is an endothelial cell-specific receptor tyrosine kinase that mediates physiological and pathological angiogenesis. We hypothesized that...