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Angel Garcia-Diaz

Explore the profile of Angel Garcia-Diaz including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 3992
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Recent Articles
1.
Delgado-Bellido D, Chacon-Barrado A, Olmedo-Pelayo J, Jordan Perez C, Gilabert-Prieto P, Diaz-Martin J, et al.
Cell Death Differ . 2025 Feb; PMID: 40000790
Uveal melanoma (UM) is the most common primary intraocular malignant tumor in adults and is where Vasculogenic Mimicry (VM) was first described. VM enables aggressive cancer cells to independently form...
2.
Fernandez-Cortes M, Delgado-Bellido D, Bermudez-Jimenez E, Paramio J, OValle F, Vinckier S, et al.
J Pathol . 2022 Dec; 259(3):318-330. PMID: 36484652
Vasculogenic mimicry (VM) describes the ability of highly aggressive tumor cells to develop pseudovascular structures without the participation of endothelial cells. PARP1 is implicated in the activation of hypoxia-inducible factors,...
3.
Delgado-Bellido D, Garcia-Diaz A, Oliver F
Methods Mol Biol . 2022 Jun; 2514:61-72. PMID: 35771419
Aberrant extravascular expression of VE-cadherin has been observed in metastasis associated with vasculogenic mimicry (VM); we have recently shown that in VM prone cells VE-cadherin (mainly in the form of...
4.
Herrera-Campos A, Zamudio-Martinez E, Delgado-Bellido D, Fernandez-Cortes M, Montuenga L, Oliver F, et al.
Cancers (Basel) . 2022 Jun; 14(11). PMID: 35681719
Hyperoxia is used in order to counteract hypoxia effects in the TME (tumor microenvironment), which are described to boost the malignant tumor phenotype and poor prognosis. The reduction of tumor...
5.
Majuelos-Melguizo J, Rodriguez-Vargas J, Martinez-Lopez N, Delgado-Bellido D, Garcia-Diaz A, Yuste V, et al.
Cancers (Basel) . 2022 Feb; 14(3). PMID: 35158994
Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor in adults. Poly (ADP-ribose) polymerase inhibitors (PARPi) represent a new class of anti-neoplastic drugs. In the current study,...
6.
Marti J, Garcia-Diaz A, Delgado-Bellido D, OValle F, Gonzalez-Flores A, Carlevaris O, et al.
Redox Biol . 2021 Feb; 41:101885. PMID: 33581682
Background: The adaptation to hypoxia is mainly controlled by the HIF transcription factors. Increased expression/activity of HIF-1α correlates with poor prognosis in cancer patients. PARP-1 inhibitors are used in the...
7.
Torrejon D, Abril-Rodriguez G, Champhekar A, Tsoi J, Campbell K, Kalbasi A, et al.
Cancer Discov . 2020 May; 10(8):1140-1157. PMID: 32467343
Mechanism-based strategies to overcome resistance to PD-1 blockade therapy are urgently needed. We developed genetic acquired resistant models of , and loss-of-function mutations by gene knockout in human and murine...
8.
Marti J, Fernandez-Cortes M, Serrano-Saenz S, Zamudio-Martinez E, Delgado-Bellido D, Garcia-Diaz A, et al.
Cancers (Basel) . 2020 Apr; 12(3). PMID: 32245040
Poly(ADP-ribose) polymerases (PARPs), represent a family of 17 proteins implicated in a variety of cell functions; some of them possess the enzymatic ability to synthesize and attach poly (ADP-ribose) (also...
9.
Delgado-Bellido D, Bueno-Galera C, Lopez-Jimenez L, Garcia-Diaz A, Oliver F
Front Oncol . 2020 Mar; 10:18. PMID: 32117706
Aberrant extra-vascular expression of VE-cadherin has been observed in metastasis associated with Vasculogenic Mimicry (VM); we have recently shown that in VM prone cells VE-cadherin is mainly in the form...
10.
Garcia-Diaz A, Shin D, Moreno B, Saco J, Escuin-Ordinas H, Rodriguez G, et al.
Cell Rep . 2019 Dec; 29(11):3766. PMID: 31825850
No abstract available.