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Andy J Fischer

Explore the profile of Andy J Fischer including associated specialties, affiliations and a list of published articles. Areas
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Articles 79
Citations 2605
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Recent Articles
1.
Taylor O, DeGroff N, El-Hodiri H, Gao C, Fischer A
Elife . 2025 Mar; 13. PMID: 40047533
The purpose of these studies is to investigate how Sphingosine-1-phosphate (S1P) signaling regulates glial phenotype, dedifferentiation of Müller glia (MG), reprogramming into proliferating MG-derived progenitor cells (MGPCs), and neuronal differentiation...
2.
Taylor O, Kelly L, El-Hodiri H, Fischer A
bioRxiv . 2025 Feb; PMID: 39975061
The purpose of this study was to investigate how Sphingosine-1-phosphate (S1P) signaling regulates glial phenotype, neuroprotection, and reprogramming of Müller glia (MG) into neurogenic MG-derived progenitor cells (MGPCs) in the...
3.
Hamadmad S, Heisler-Taylor T, Goswami S, Hawthorn E, Chaurasia S, Martini D, et al.
Glia . 2025 Feb; PMID: 39916387
Ibudilast, an inhibitor of macrophage migration inhibitory factor (MIF) and phosphodiesterase (PDE), has been recently shown to have neuroprotective effects in a variety of neurologic diseases. We utilize a chick...
4.
Taylor O, El-Hodiri H, Palazzo I, Todd L, Fischer A
Glia . 2024 Oct; 73(1):4-24. PMID: 39448874
We summarize recent findings in different animal models regarding the different cell-signaling pathways and gene networks that influence the reprogramming of Müller glia into proliferating, neurogenic progenitor cells in the...
5.
Taylor O, DeGroff N, DeGroff N, El-Hodiri H, Gao C, Fischer A
bioRxiv . 2024 Aug; PMID: 39149287
The purpose of these studies is to investigate how Sphingosine-1-phosphate (S1P) signaling regulates glial phenotype, dedifferentiation of Müller glia (MG), reprogramming into proliferating MG-derived progenitor cells (MGPCs), and neuronal differentiation...
6.
Kelly L, El-Hodiri H, Crider A, Fischer A
Mol Cell Neurosci . 2024 Apr; 129:103932. PMID: 38679247
Different kinase-dependent cell signaling pathways are known to play important roles in glia-mediated neuroprotection and reprogramming of Müller glia (MG) into Müller glia-derived progenitor cells (MGPCs) in the retina. However,...
7.
Hamadmad S, Heisler-Taylor T, Goswami S, Hawthorn E, Chaurasia S, Martini D, et al.
bioRxiv . 2024 Apr; PMID: 38562805
Ibudilast, an inhibitor of macrophage migration inhibitory factor (MIF) and phosphodiesterase (PDE), has been recently shown to have neuroprotective effects in a variety of neurologic diseases. We utilize a chick...
8.
Taylor O, Patel S, Hawthorn E, El-Hodiri H, Fischer A
Glia . 2024 Mar; 72(7):1236-1258. PMID: 38515287
The purpose of this study was to investigate how ID factors regulate the ability of Müller glia (MG) to reprogram into proliferating MG-derived progenitor cells (MGPCs) in the chick retina....
9.
Kelly L, El-Hodiri H, Crider A, Fischer A
bioRxiv . 2024 Jan; PMID: 38168320
Different kinase-dependent cell signaling pathways are known to play important roles in glia-mediated neuroprotection and reprogramming of Müller glia (MG) into Müller glia-derived progenitor cells (MGPCs) in the retina. However,...
10.
El-Hodiri H, Bentley J, Reske A, Taylor O, Palazzo I, Campbell W, et al.
Development . 2023 Nov; 150(23). PMID: 37971210
Recent studies have demonstrated the impact of pro-inflammatory signaling and reactive microglia/macrophages on the formation of Müller glial-derived progenitor cells (MGPCs) in the retina. In chick retina, ablation of microglia/macrophages...