Andrey L Karamyshev
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Explore the profile of Andrey L Karamyshev including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
483
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Recent Articles
1.
Jaramillo-Martinez V, Sennoune S, Tikhonova E, Karamyshev A, Ganapathy V, Urbatsch I
J Mol Biol
. 2024 Oct;
436(22):168820.
PMID: 39442909
The sodium-coupled citrate transporter (NaCT, SLC13A5) mediates citrate uptake across the plasma membrane via an inward Na gradient. Mutations in SLC13A5 cause early infantile epileptic encephalopathy type-25 (EIEE25, SLC13A5 Epilepsy)...
2.
Jaramillo-Martinez V, Sennoune S, Tikhonova E, Karamyshev A, Ganapathy V, Urbatsch I
bioRxiv
. 2024 Jun;
PMID: 38826402
Summary: Loss-of-function mutations in the SLC13A5 causes SLC13A5-Epilepsy, a devastating disease characterized by neonatal epilepsy. Currently no cure is available. We clarify the molecular-level defects to guide future developments for...
3.
Miller S, Tikhonova E, Hernandez S, Dufour J, Karamyshev A
J Mol Biol
. 2024 Feb;
436(6):168492.
PMID: 38360088
Many insulin gene variants alter the protein sequence and result in monogenic diabetes due to insulin insufficiency. However, the molecular mechanisms of various disease-causing mutations are unknown. Insulin is synthesized...
4.
Kunze M, Alder N, Hwang I, Roussel G, Karamyshev A
Front Physiol
. 2023 Dec;
14:1338852.
PMID: 38143916
No abstract available.
5.
Wang T, Tian S, Tikhonova E, Karamyshev A, Wang J, Zhang F, et al.
Biology (Basel)
. 2023 Dec;
12(12).
PMID: 38132362
miRNAs moderately inhibit the translation and enhance the degradation of their target mRNAs via cognate binding sites located predominantly in the 3'-untranslated regions (UTR). Paradoxically, miRNA targets are also polysome-associated....
6.
Guarnizo S, Kellogg M, Miller S, Tikhonova E, Karamysheva Z, Karamyshev A
NAR Genom Bioinform
. 2023 Oct;
5(4):lqad093.
PMID: 37859801
Secreted and membrane proteins represent a third of all cellular proteins and contain N-terminal signal peptides that are required for protein targeting to endoplasmic reticulum (ER). Mutations in signal peptides...
7.
Orobets K, Karamyshev A
Int J Mol Sci
. 2023 Oct;
24(19).
PMID: 37834241
Alzheimer's disease (AD) is one of the most common neurodegenerative disorders associated with age or inherited mutations. It is characterized by severe dementia in the late stages that affect memory,...
8.
Karamysheva Z, Karamyshev A
Front Cell Dev Biol
. 2023 Jun;
11:1198184.
PMID: 37346176
No abstract available.
9.
Guarnizo S, Tikhonova E, Karamyshev A, Muskus C, Karamysheva Z
Nat Commun
. 2023 May;
14(1):2605.
PMID: 37147291
Leishmania is a unicellular protozoan that has a limited transcriptional control and mostly uses post-transcriptional regulation of gene expression, although the molecular mechanisms of the process are still poorly understood....
10.
Rodriguez-Almonacid C, Kellogg M, Karamyshev A, Karamysheva Z
Int J Mol Sci
. 2023 Apr;
24(8).
PMID: 37108644
Ribosomes, in general, are viewed as constitutive macromolecular machines where protein synthesis takes place; however, this view has been recently challenged, supporting the hypothesis of ribosome specialization and opening a...