Andrew S MacDonald
Overview
Explore the profile of Andrew S MacDonald including associated specialties, affiliations and a list of published articles.
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95
Citations
3948
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Recent Articles
1.
Cook P, Brown S, Houlder E, Furlong-Silva J, Conn D, Colombo S, et al.
Nat Commun
. 2025 Jan;
16(1):928.
PMID: 39843887
Fungal spores are abundant in the environment and a major cause of asthma. Originally characterised as a type 2 inflammatory disease, allergic airway inflammation that underpins asthma can also involve...
2.
Houlder E, Gago S, Vere G, Furlong-Silva J, Conn D, Hickey E, et al.
J Allergy Clin Immunol
. 2024 Nov;
155(3):988-1001.
PMID: 39581297
Background: Exposure to fungi, especially Aspergillus fumigatus, can elicit potent allergic inflammation that triggers and worsens asthmatic disease. Dendritic cells (DCs) initiate allergic inflammatory responses to allergic stimuli. However, it...
3.
Dookie R, Villegas-Mendez A, Cheeseman A, Jones A, Barroso R, Barrett J, et al.
Infect Immun
. 2024 Sep;
92(11):e0034524.
PMID: 39324794
Pro-inflammatory immune responses are rapidly suppressed during blood-stage malaria but the molecular mechanisms driving this regulation are still incompletely understood. In this study, we show that the co-inhibitory receptors TIGIT...
4.
Desmond L, Holbrook E, Wright C, Zambrano C, Stamper C, Bohr A, et al.
Int J Mol Sci
. 2024 Jan;
25(1).
PMID: 38203645
Previous studies have shown that the in vivo administration of soil-derived bacteria with anti-inflammatory and immunoregulatory properties, such as NCTC 11659, can prevent a stress-induced shift toward an inflammatory M1...
5.
Ridley A, Ou Y, Karlsson R, Pun N, Birchenough H, Mulholland I, et al.
Sci Signal
. 2023 Nov;
16(810):eadf2537.
PMID: 37934811
Chemokine-driven leukocyte recruitment is a key component of the immune response and of various diseases. Therapeutically targeting the chemokine system in inflammatory disease has been unsuccessful, which has been attributed...
6.
Costain A, Phythian-Adams A, Colombo S, Marley A, Owusu C, Cook P, et al.
Front Immunol
. 2023 Sep;
14:1229665.
PMID: 37675098
[This corrects the article DOI: 10.3389/fimmu.2022.906338.].
7.
Colombo S, Brown S, Hepworth M, Hankinson J, Granato F, Kitchen S, et al.
Discov Immunol
. 2023 Aug;
2(1):kyad009.
PMID: 37545765
The lung is a dynamic mucosal surface constantly exposed to a variety of immunological challenges including harmless environmental antigens, pollutants, and potentially invasive microorganisms. Dysregulation of the immune system at...
8.
Holbrook E, Zambrano C, Wright C, Dube E, Stewart J, Sanders W, et al.
Int J Mol Sci
. 2023 Mar;
24(6).
PMID: 36982250
Inflammatory conditions, including allergic asthma and conditions in which chronic low-grade inflammation is a risk factor, such as stress-related psychiatric disorders, are prevalent and are a significant cause of disability...
9.
Finlay C, Parkinson J, Zhang L, Chan B, Ajendra J, Chenery A, et al.
Immunity
. 2023 Mar;
56(5):1064-1081.e10.
PMID: 36948193
The recent revolution in tissue-resident macrophage biology has resulted largely from murine studies performed in C57BL/6 mice. Here, using both C57BL/6 and BALB/c mice, we analyze immune cells in the...
10.
Stark K, Rinaldi G, Cortes A, Costain A, MacDonald A, Cantacessi C
Parasite Immunol
. 2023 Jan;
45(4):e12970.
PMID: 36655799
The pathophysiology of schistosomiasis is linked to the formation of fibrous granulomas around eggs that become trapped in host tissues, particularly the intestines and liver, during their migration to reach...