Alexander T Phythian-Adams
Overview
Explore the profile of Alexander T Phythian-Adams including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
14
Citations
606
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Costain A, Phythian-Adams A, Colombo S, Marley A, Owusu C, Cook P, et al.
Front Immunol
. 2023 Sep;
14:1229665.
PMID: 37675098
[This corrects the article DOI: 10.3389/fimmu.2022.906338.].
2.
Costain A, Phythian-Adams A, Colombo S, Marley A, Owusu C, Cook P, et al.
Front Immunol
. 2022 Aug;
13:906338.
PMID: 35958580
Schistosomiasis is a disease of global significance, with severity and pathology directly related to how the host responds to infection. The immunological narrative of schistosomiasis has been constructed through decades...
3.
Webb L, Phythian-Adams A, Costain A, Brown S, Lundie R, Forde-Thomas J, et al.
Immunohorizons
. 2021 Aug;
5(8):721-732.
PMID: 34462311
Plasmacytoid dendritic cells (pDCs) are potent producers of type I IFN (IFN-I) during viral infection and respond to IFN-I in a positive feedback loop that promotes their function. IFN-I shapes...
4.
Jones G, Brown S, Phythian-Adams A, Ivens A, Cook P, MacDonald A
Front Immunol
. 2020 Mar;
11:183.
PMID: 32117307
Methyl-CpG-binding domain-2 (Mbd2) acts as an epigenetic regulator of gene expression, by linking DNA methylation to repressive chromatin structure. Although Mbd2 is widely expressed in gastrointestinal immune cells and is...
5.
OSullivan J, Behnsen J, Starborg T, MacDonald A, Phythian-Adams A, Else K, et al.
Parasitology
. 2017 Nov;
145(7):848-854.
PMID: 29179788
X-ray micro-computed tomography (μCT) is a technique which can obtain three-dimensional images of a sample, including its internal structure, without the need for destructive sectioning. Here, we review the capability...
6.
Webb L, Lundie R, Borger J, Brown S, Connor L, Cartwright A, et al.
EMBO J
. 2017 Jul;
36(16):2404-2418.
PMID: 28716804
Type 2 inflammation is a defining feature of infection with parasitic worms (helminths), as well as being responsible for widespread suffering in allergies. However, the precise mechanisms involved in T...
7.
Lundie R, Webb L, Marley A, Phythian-Adams A, Cook P, Jackson-Jones L, et al.
Immunol Cell Biol
. 2015 Dec;
94(4):400-10.
PMID: 26657145
Dendritic cells (DCs) are the key initiators of T-helper (Th) 2 immune responses against the parasitic helminth Schistosoma mansoni. Although the liver is one of the main sites of antigen...
8.
Cook P, Owen H, Deaton A, Borger J, Brown S, Clouaire T, et al.
Nat Commun
. 2015 Apr;
6:6920.
PMID: 25908537
Dendritic cells (DCs) direct CD4(+) T-cell differentiation into diverse helper (Th) subsets that are required for protection against varied infections. However, the mechanisms used by DCs to promote Th2 responses,...
9.
Jones L, Cook P, Ivens A, Thomas G, Phythian-Adams A, Allen J, et al.
Int Immunol
. 2015 Apr;
27(11):589-96.
PMID: 25899567
The archetypal Th2 cytokine IL-4 has previously been shown to alternatively activate murine macrophages and, more recently, dendritic cells (DCs) both in vitro and in vivo. IL-4 has also been...
10.
Mylonas K, Jenkins S, Castellan R, Ruckerl D, McGregor K, Phythian-Adams A, et al.
Immunobiology
. 2015 Feb;
220(7):924-33.
PMID: 25700973
Tissue resident macrophages have vital homeostatic roles in many tissues but their roles are less well defined in the heart. The present study aimed to identify the density, polarisation status...