Andrew Plumridge
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Explore the profile of Andrew Plumridge including associated specialties, affiliations and a list of published articles.
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11
Citations
341
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Recent Articles
1.
Andersen J, Dalhus B, Viuff D, Thue Ravn B, Gunnarsen K, Plumridge A, et al.
J Biol Chem
. 2014 Mar;
289(19):13492-502.
PMID: 24652290
A major challenge for the therapeutic use of many peptides and proteins is their short circulatory half-life. Albumin has an extended serum half-life of 3 weeks because of its size...
2.
Andersen J, Cameron J, Plumridge A, Evans L, Sleep D, Sandlie I
J Biol Chem
. 2013 Jul;
288(33):24277-85.
PMID: 23818524
Albumin has a serum half-life of 3 weeks in humans. This has been utilized to extend the serum persistence of biopharmaceuticals that are fused to albumin. In light of the...
3.
Stratford M, Plumridge A, Pleasants M, Novodvorska M, Baker-Glenn C, Pattenden G, et al.
Int J Food Microbiol
. 2012 Jun;
157(3):375-83.
PMID: 22726726
Moulds are able to cause spoilage in preserved foods through degradation of the preservatives using the Pad-decarboxylation system. This causes, for example, decarboxylation of the preservative sorbic acid to 1,3-pentadiene,...
4.
Andersen J, Dalhus B, Cameron J, Daba M, Plumridge A, Evans L, et al.
Nat Commun
. 2012 Jan;
3:610.
PMID: 22215085
Albumin is the most abundant protein in blood where it has a pivotal role as a transporter of fatty acids and drugs. Like IgG, albumin has long serum half-life, protected...
5.
Plumridge A, Melin P, Stratford M, Novodvorska M, Shunburne L, Dyer P, et al.
Fungal Genet Biol
. 2010 May;
47(8):683-92.
PMID: 20452450
The ability to resist anti-microbial compounds is of key evolutionary benefit to microorganisms. Aspergillus niger has previously been shown to require the activity of a phenylacrylic acid decarboxylase (encoded by...
6.
Stratford M, Plumridge A, Nebe-von-Caron G, Archer D
Int J Food Microbiol
. 2009 Oct;
136(1):37-43.
PMID: 19846233
Fungal spoilage of many foods is prevented by weak-acid preservatives such as sorbic acid or acetic acid. We show that sorbic and acetic acids do not both inhibit cells by...
7.
Wimalasena T, Enjalbert B, Guillemette T, Plumridge A, Budge S, Yin Z, et al.
Fungal Genet Biol
. 2008 Jul;
45(9):1235-47.
PMID: 18602013
The unfolded protein response (UPR) regulates the expression of genes involved in the protein secretory pathway and in endoplasmic reticulum (ER) stress in yeasts and filamentous fungi. We have characterized...
8.
Melin P, Stratford M, Plumridge A, Archer D
Microbiology (Reading)
. 2008 Apr;
154(Pt 4):1251-1257.
PMID: 18375817
Weak-acid preservatives such as sorbic acid are added to foods to prevent fungal spoilage. The modes of action of weak-acid preservatives are only partially understood and, in this paper, further...
9.
Plumridge A, Stratford M, Lowe K, Archer D
Appl Environ Microbiol
. 2007 Nov;
74(2):550-2.
PMID: 18039817
Resistance to sorbic and cinnamic acids is mediated by a phenylacrylic acid decarboxylase (PadA1) in Aspergillus niger. A. niger DeltapadA1 mutants are unable to decarboxylate sorbic and cinnamic acids, and...
10.
Stratford M, Plumridge A, Archer D
Appl Environ Microbiol
. 2007 Sep;
73(20):6534-42.
PMID: 17766451
The spoilage yeast Saccharomyces cerevisiae degraded the food preservative sorbic acid (2,4-hexadienoic acid) to a volatile hydrocarbon, identified by gas chromatography mass spectrometry as 1,3-pentadiene. The gene responsible was identified...