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Andrew P Voigt

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Articles 39
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Recent Articles
1.
Mulfaul K, Khan A, Schwarte S, Voigt A, Moore R, Potempa L, et al.
Invest Ophthalmol Vis Sci . 2024 Dec; 65(14):15. PMID: 39641748
Purpose: Choroidal inflammation, complement deposition, and accumulation of C-reactive protein (CRP) are involved in age-related macular degeneration (AMD) pathology. The pro-inflammatory signals that regulate immune cell recruitment in the choroid...
2.
Sterling J, Rajesh A, Droho S, Gong J, Wang A, Voigt A, et al.
J Clin Invest . 2024 Aug; 134(20). PMID: 39207852
The blood-retina barrier (BRB), which is disrupted in diabetic retinopathy (DR) and uveitis, is an important anatomical characteristic of the retina, regulating nutrient, waste, water, protein, and immune cell flux....
3.
Mullin N, Bohrer L, Voigt A, Lozano L, Wright A, Bonilha V, et al.
J Clin Invest . 2024 Apr; 134(11). PMID: 38652563
While dysfunction and death of light-detecting photoreceptor cells underlie most inherited retinal dystrophies, knowledge of the species-specific details of human rod and cone photoreceptor cell development remains limited. Here, we...
4.
Voigt A, Mullin N, Navratil E, Flamme-Wiese M, Lin L, Scheetz T, et al.
Invest Ophthalmol Vis Sci . 2023 Oct; 64(13):40. PMID: 37878301
Purpose: Macular neovascularization is a relatively common and potentially visually devastating complication of age-related macular degeneration. In macular neovascularization, pathologic angiogenesis can originate from either the choroid or the retina,...
5.
Droho S, Voigt A, Sterling J, Rajesh A, Chan K, Cuda C, et al.
J Neuroinflammation . 2023 Oct; 20(1):238. PMID: 37858232
Background: Neovascular age-related macular degeneration causes vision loss from destructive angiogenesis, termed choroidal neovascularization (CNV). Cx3cr1 mice display alterations in non-classical monocytes and microglia with increased CNV size, suggesting that...
6.
Voigt A, Mullin N, Navratil E, Flamme-Wiese M, Lin L, Scheetz T, et al.
bioRxiv . 2023 Jul; PMID: 37398429
Macular neovascularization is a relatively common and potentially visually devastating complication of age-related macular degeneration. In macular neovascularization, pathologic angiogenesis can originate from either the choroid or the retina, but...
7.
Mullin N, Voigt A, Flamme-Wiese M, Liu X, Riker M, Varzavand K, et al.
JCI Insight . 2023 Jun; 8(14). PMID: 37289546
Variants within the high copy number mitochondrial genome (mtDNA) can disrupt organelle function and lead to severe multisystem disease. The wide range of manifestations observed in patients with mitochondrial disease...
8.
Cooke J, Voigt A, Collingwood M, Stone N, Whitmore S, DeLuca A, et al.
Stem Cells Transl Med . 2023 May; 12(6):365-378. PMID: 37221451
Prior to use, newly generated induced pluripotent stem cells (iPSC) should be thoroughly validated. While excellent validation and release testing assays designed to evaluate potency, genetic integrity, and sterility exist,...
9.
Bohrer L, Stone N, Mullin N, Voigt A, Anfinson K, Fick J, et al.
J Transl Med . 2023 Mar; 21(1):161. PMID: 36855199
Background: Inherited retinal degeneration is a leading cause of incurable vision loss in the developed world. While autologous iPSC mediated photoreceptor cell replacement is theoretically possible, the lack of commercially...
10.
Mullin N, Voigt A, Boese E, Liu X, Stone E, Tucker B, et al.
Am J Pathol . 2023 Feb; 193(11):1750-1761. PMID: 36775060
Some human retinal diseases are characterized by pathology that is restricted to specific cell types and to specific regions of the eye. Several disease entities either selectively affect or spare...