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Andrew P Seddon

Explore the profile of Andrew P Seddon including associated specialties, affiliations and a list of published articles. Areas
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Citations 405
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Recent Articles
1.
Cunningham D, Danley D, Geoghegan K, Griffor M, Hawkins J, Subashi T, et al.
Nat Struct Mol Biol . 2007 Apr; 14(5):413-9. PMID: 17435765
Proprotein convertase subtilisin kexin type 9 (PCSK9) lowers the abundance of surface low-density lipoprotein (LDL) receptor through an undefined mechanism. The structure of human PCSK9 shows the subtilisin-like catalytic site...
2.
Qiu X, Mistry A, Ammirati M, Chrunyk B, Clark R, Cong Y, et al.
Nat Struct Mol Biol . 2007 Jan; 14(2):106-13. PMID: 17237796
Cholesteryl ester transfer protein (CETP) shuttles various lipids between lipoproteins, resulting in the net transfer of cholesteryl esters from atheroprotective, high-density lipoproteins (HDL) to atherogenic, lower-density species. Inhibition of CETP...
3.
Liu S, Knafels J, Chang J, Waszak G, Baldwin E, Deibel Jr M, et al.
J Biol Chem . 2006 Apr; 281(26):18193-200. PMID: 16638752
Herpesviruses are the second leading cause of human viral diseases. Herpes Simplex Virus types 1 and 2 and Varicella-zoster virus produce neurotropic infections such as cutaneous and genital herpes, chickenpox,...
4.
Pauly T, Sulea T, Ammirati M, Sivaraman J, Danley D, Griffor M, et al.
Biochemistry . 2003 Mar; 42(11):3203-13. PMID: 12641451
Cathepsin S, a lysosomal cysteine protease of the papain superfamily, has been implicated in the preparation of MHC class II alphabeta-heterodimers for antigen presentation to CD4+ T lymphocytes and is...