Andrew N Hoofnagle
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Explore the profile of Andrew N Hoofnagle including associated specialties, affiliations and a list of published articles.
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268
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6419
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Recent Articles
11.
Rappold B, Hoofnagle A
Clin Mass Spectrom
. 2024 Aug;
3:13-21.
PMID: 39193099
Mass spectrometry provides considerable benefits over other analytical techniques due to advantages imparted by the use of isotopically labeled internal standards. In some analytical approaches, the internal standard provides reference...
12.
Moseholm K, Cronje H, Koch M, Fitzpatrick A, Lopez O, de Oliveira Otto M, et al.
Alzheimers Dement (Amst)
. 2024 Aug;
16(3):e12623.
PMID: 39130802
Introduction: Whether circulating levels of sphingolipids are prospectively associated with cognitive decline and dementia risk is uncertain. Methods: We measured 14 sphingolipid species in plasma samples from 4488 participants (mean...
13.
Liu C, Wu K, Choi H, Han H, Zhang X, Watson J, et al.
bioRxiv
. 2024 Jul;
PMID: 39071267
Proteins which bind intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) with high affinity and specificity could have considerable utility for therapeutic and diagnostic applications. However, a general methodology...
14.
Li J, Hatten-Beck M, Lee J, Hoofnagle A
Endocrine
. 2024 Jul;
87(1):79-84.
PMID: 39030378
Background: To address the challenges posed by inconsistent detection of analog insulin in commercially available insulin immunoassays, resulting in potential discrepancies in clinical findings and misdiagnosis during the investigation of...
15.
Chan K, Yamaguchi D, Treger R, Hoofnagle A, Liao H
Clin Chim Acta
. 2024 Jun;
560:119756.
PMID: 38825058
Background: Iron studies are critical for diagnosing iron deficiency and hemochromatosis. We present a case exhibiting macrocytic anemia with perplexingly high plasma iron concentrations. Methods And Results: The initial clinical...
16.
Moseholm K, Horn J, Fitzpatrick A, Djousse L, Longstreth Jr W, Lopez O, et al.
Front Neurol
. 2024 May;
15:1385623.
PMID: 38765262
Background: Sphingolipids are implicated in neurodegeneration and neuroinflammation. We assessed the potential role of circulating ceramides and sphingomyelins in subclinical brain pathology by investigating their association with brain magnetic resonance...
17.
Tsantilas K, Merrihew G, Robbins J, Johnson R, Park J, Plubell D, et al.
bioRxiv
. 2024 Apr;
PMID: 38645098
A thorough evaluation of the quality, reproducibility, and variability of bottom-up proteomics data is necessary at every stage of a workflow from planning to analysis. We share vignettes applying adaptable...
18.
Wu C, Tsantilas K, Park J, Plubell D, Sanders J, Naicker P, et al.
bioRxiv
. 2024 Apr;
PMID: 38617345
Membrane-bound particles in plasma are composed of exosomes, microvesicles, and apoptotic bodies and represent ~1-2% of the total protein composition. Proteomic interrogation of this subset of plasma proteins augments the...
19.
Moradian A, Goonatilleke E, Lin T, Hatten-Beck M, Emrick M, Schepmoes A, et al.
Clin Chem
. 2024 Mar;
70(6):855-864.
PMID: 38549041
Background: The enhanced precision and selectivity of liquid chromatography-tandem mass spectrometry (LC-MS/MS) makes it an attractive alternative to certain clinical immunoassays. Easily transferrable work flows could help facilitate harmonization and...
20.
Hsu S, Bansal N, Denburg M, Ginsberg C, Hoofnagle A, Isakova T, et al.
J Bone Miner Res
. 2024 Mar;
39(4):433-442.
PMID: 38477777
Fracture risk is high in chronic kidney disease (CKD) and underlying pathophysiology and risk factors may differ from the general population. In a cohort study of 3939 participants in the...