Andrew M Gross
Overview
Explore the profile of Andrew M Gross including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
1098
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0
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Recent Articles
1.
Dolzhenko E, Bennett M, Richmond P, Trost B, Chen S, van Vugt J, et al.
Genome Biol
. 2020 Apr;
21(1):102.
PMID: 32345345
Repeat expansions are responsible for over 40 monogenic disorders, and undoubtedly more pathogenic repeat expansions remain to be discovered. Existing methods for detecting repeat expansions in short-read sequencing data require...
2.
Helman G, Lajoie B, Crawford J, Takanohashi A, Walkiewicz M, Dolzhenko E, et al.
Ann Clin Transl Neurol
. 2020 Jan;
7(1):144-152.
PMID: 31912665
Genetic white matter disorders have heterogeneous etiologies and overlapping clinical presentations. We performed a study of the diagnostic efficacy of genome sequencing in 41 unsolved cases with prior exome sequencing,...
3.
Gross A, Ajay S, Rajan V, Brown C, Bluske K, Burns N, et al.
Genet Med
. 2018 Oct;
21(5):1121-1130.
PMID: 30293986
Purpose: Current diagnostic testing for genetic disorders involves serial use of specialized assays spanning multiple technologies. In principle, genome sequencing (GS) can detect all genomic pathogenic variant types on a...
4.
Eckhardt M, Zhang W, Gross A, Von Dollen J, Johnson J, Franks-Skiba K, et al.
Cancer Discov
. 2018 Sep;
8(11):1474-1489.
PMID: 30209081
We have mapped a global network of virus-host protein interactions by purification of the complete set of human papillomavirus (HPV) proteins in multiple cell lines followed by mass spectrometry analysis....
5.
Wang T, Tsui B, Kreisberg J, Robertson N, Gross A, Yu M, et al.
Genome Biol
. 2017 Mar;
18(1):57.
PMID: 28351423
Background: Global but predictable changes impact the DNA methylome as we age, acting as a type of molecular clock. This clock can be hastened by conditions that decrease lifespan, raising...
6.
Carter H, Marty R, Hofree M, Gross A, Jensen J, Fisch K, et al.
Cancer Discov
. 2017 Feb;
7(4):410-423.
PMID: 28188128
Recent studies have characterized the extensive somatic alterations that arise during cancer. However, the somatic evolution of a tumor may be significantly affected by inherited polymorphisms carried in the germline....
7.
Srivas R, Shen J, Yang C, Sun S, Li J, Gross A, et al.
Mol Cell
. 2016 Jul;
63(3):514-25.
PMID: 27453043
An emerging therapeutic strategy for cancer is to induce selective lethality in a tumor by exploiting interactions between its driving mutations and specific drug targets. Here we use a multi-species...
8.
Gross A, Jaeger P, Kreisberg J, Licon K, Jepsen K, Khosroheidari M, et al.
Mol Cell
. 2016 Apr;
62(2):157-168.
PMID: 27105112
HIV-infected individuals are living longer on antiretroviral therapy, but many patients display signs that in some ways resemble premature aging. To investigate and quantify the impact of chronic HIV infection...
9.
Gross A, Kreisberg J, Ideker T
PLoS One
. 2015 Nov;
10(11):e0142618.
PMID: 26555223
To identify the transcriptional regulatory changes that are most widespread in solid tumors, we performed a pan-cancer analysis using over 600 pairs of tumors and adjacent normal tissues profiled in...
10.