Andrew J Schaub
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Explore the profile of Andrew J Schaub including associated specialties, affiliations and a list of published articles.
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12
Citations
110
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Recent Articles
1.
Zhao S, Schaub A, Tsai S, Luo R
J Chem Inf Model
. 2025 Feb;
65(5):2710.
PMID: 40016197
No abstract available.
2.
Reveiz M, Xu K, Lee M, Wang S, Olia A, Harris D, et al.
Front Immunol
. 2024 Nov;
15:1484029.
PMID: 39611147
Broadly neutralizing antibodies have been proposed as templates for HIV-1 vaccine design, but it has been unclear how similar vaccine-elicited antibodies are to their naturally elicited templates. To provide insight,...
3.
Wang H, Cheng C, Dal Santo J, Shen C, Bylund T, Henry A, et al.
Cell
. 2024 Oct;
187(25):7214-7231.e23.
PMID: 39471811
An antibody-based HIV-1 vaccine will require the induction of potent cross-reactive HIV-1-neutralizing responses. To demonstrate feasibility toward this goal, we combined vaccination targeting the fusion-peptide site of vulnerability with infection...
4.
Lederhofer J, Tsybovsky Y, Nguyen L, Raab J, Creanga A, Stephens T, et al.
Immunity
. 2024 Mar;
57(3):574-586.e7.
PMID: 38430907
Continuously evolving influenza viruses cause seasonal epidemics and pose global pandemic threats. Although viral neuraminidase (NA) is an effective drug and vaccine target, our understanding of the NA antigenic landscape...
5.
Kwon Y, Pegu A, Yang E, Zhang B, Bender M, Asokan M, et al.
MAbs
. 2023 Jun;
15(1):2223350.
PMID: 37345226
The amino-acid composition of the immunoglobulin variable region has been observed to impact antibody pharmacokinetics (PK). Here, we sought to improve the PK of the broad HIV-1-neutralizing VRC01-class antibodies, VRC07-523LS...
6.
Fisher C, Peter K, Newton S, Schaub A, Sobus J
Anal Bioanal Chem
. 2022 Jul;
414(22):6455-6471.
PMID: 35796784
Non-targeted analysis (NTA) using high-resolution mass spectrometry has enabled the detection and identification of unknown and unexpected compounds of interest in a wide range of sample matrices. Despite these benefits...
7.
Zhao S, Schaub A, Tsai S, Luo R
J Chem Inf Model
. 2021 Feb;
61(2):856-868.
PMID: 33534558
Pantetheine is ubiquitous in nature in various forms of pantetheine-containing ligands (PCLs), including coenzyme A and phosphopantetheine. Lack of scalable force field libraries for PCLs has hampered the computational studies...
8.
Favela K, Hartnett M, Janssen J, Vickers D, Schaub A, Spidle H, et al.
J Am Soc Mass Spectrom
. 2021 Jan;
32(4):860-871.
PMID: 33395529
Masks constructed of a variety of materials are in widespread use due to the COVID-19 pandemic, and people are exposed to chemicals inherent in the masks through inhalation. This work...
9.
Milligan J, Lee D, Jackson D, Schaub A, Beld J, Barajas J, et al.
Nat Chem Biol
. 2019 Jun;
15(7):669-671.
PMID: 31209348
Fatty acid synthases are dynamic ensembles of enzymes that can biosynthesize long hydrocarbon chains efficiently. Here we visualize the interaction between the Escherichia coli acyl carrier protein (AcpP) and β-ketoacyl-ACP-synthase...
10.
Schaub A, Moreno G, Zhao S, Truong H, Luo R, Tsai S
Methods Enzymol
. 2019 Jun;
622:375-409.
PMID: 31155062
Various computational methodologies can be applied to enzymological studies on enzymes in the fatty acid, polyketide, and non-ribosomal peptide biosynthetic pathways. These multi-domain complexes are called fatty acid synthases, polyketide...