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Andrew J Dwork

Explore the profile of Andrew J Dwork including associated specialties, affiliations and a list of published articles. Areas
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Articles 90
Citations 5200
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Recent Articles
1.
Chen Y, Chauhan S, Gong C, Dayton H, Xu C, De La Cruz E, et al.
Nat Biomed Eng . 2024 Aug; 8(9):1109-1123. PMID: 39209948
Light-sheet fluorescence microscopy (LSFM) is a widely used technique for imaging cleared tissue and living samples. However, high-performance LSFM systems are typically expensive and not easily scalable. Here we introduce...
2.
Bransfield R, Gadila S, Kursawe L, Dwork A, Rosoklija G, Horn E, et al.
Heliyon . 2024 May; 10(10):e31159. PMID: 38779029
Background: Infectious diseases can contribute to substance abuse. Here, a fatal case of borreliosis and substance abuse is reported. This patient had a history of multiple tick bites and increasing...
3.
Mosharov E, Rosenberg A, Monzel A, Osto C, Stiles L, Rosoklija G, et al.
Res Sq . 2024 Apr; PMID: 38562777
Mitochondrial oxidative phosphorylation (OxPhos) powers brain activity, and mitochondrial defects are linked to neurodegenerative and neuropsychiatric disorders, underscoring the need to define the brain's molecular energetic landscape. To bridge the...
4.
Mosharov E, Rosenberg A, Monzel A, Osto C, Stiles L, Rosoklija G, et al.
bioRxiv . 2024 Mar; PMID: 38496679
Mitochondrial oxidative phosphorylation (OxPhos) powers brain activity, and mitochondrial defects are linked to neurodegenerative and neuropsychiatric disorders, underscoring the need to define the brain's molecular energetic landscape. To bridge the...
5.
Sun S, Liu Q, Wang Z, Huang Y, Sublette M, Dwork A, et al.
Mol Psychiatry . 2024 Jan; 29(5):1417-1426. PMID: 38278992
Human genetic studies indicate that suicidal ideation and behavior are both heritable. Most studies have examined associations between aberrant gene expression and suicide behavior, but behavior risk is linked to...
6.
Ruff D, Balbo I, Lai R, Dieng D, Hennessey C, Vennam K, et al.
Ann Clin Transl Neurol . 2023 Dec; 11(2):377-388. PMID: 38098226
Objective: Postmortem examination of the essential tremor cerebellum has revealed a variety of pathological changes centered in and around Purkinje cells. Studies have predominantly focused on cerebellar neuronal connections. Bergmann...
7.
Underwood M, Galfalvy H, Hsiung S, Liu Y, Simpson N, Bakalian M, et al.
Int J Neuropsychopharmacol . 2023 May; 26(7):501-512. PMID: 37243534
Background: The hypothalamic-pituitary-adrenal (HPA) axis is a major stress response system, and excessive HPA responses can impact major depressive disorder and suicide. We examined relationships between reported early-life adversity (ELA),...
8.
Zhang D, Deng Y, Kukanja P, Agirre E, Bartosovic M, Dong M, et al.
Nature . 2023 Mar; 616(7955):113-122. PMID: 36922587
Emerging spatial technologies, including spatial transcriptomics and spatial epigenomics, are becoming powerful tools for profiling of cellular states in the tissue context. However, current methods capture only one layer of...
9.
Soung A, Vanderheiden A, Nordvig A, Sissoko C, Canoll P, Mariani M, et al.
Brain . 2022 Aug; 145(12):4193-4201. PMID: 36004663
Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated with acute and postacute cognitive and neuropsychiatric symptoms including impaired memory, concentration, attention, sleep and affect. Mechanisms underlying...
10.
Deng Y, Bartosovic M, Ma S, Zhang D, Kukanja P, Xiao Y, et al.
Nature . 2022 Aug; 609(7926):375-383. PMID: 35978191
Cellular function in tissue is dependent on the local environment, requiring new methods for spatial mapping of biomolecules and cells in the tissue context. The emergence of spatial transcriptomics has...