Andrew J Dwork
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Explore the profile of Andrew J Dwork including associated specialties, affiliations and a list of published articles.
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90
Citations
5200
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Recent Articles
11.
Ammothumkandy A, Ravina K, Wolseley V, Tartt A, Yu P, Corona L, et al.
Nat Neurosci
. 2022 Apr;
25(4):493-503.
PMID: 35383330
The hippocampus is the most common seizure focus in people. In the hippocampus, aberrant neurogenesis plays a critical role in the initiation and progression of epilepsy in rodent models, but...
12.
Chatterton Z, Mendelev N, Chen S, Carr W, Kamimori G, Ge Y, et al.
Front Mol Neurosci
. 2021 Jul;
14:672614.
PMID: 34276305
Sampling the live brain is difficult and dangerous, and withdrawing cerebrospinal fluid is uncomfortable and frightening to the subject, so new sources of real-time analysis are constantly sought. Cell-free DNA...
13.
Gadila S, Rosoklija G, Dwork A, Fallon B, Embers M
Front Neurol
. 2021 May;
12:628045.
PMID: 34040573
The complex etiology of neurodegenerative disease has prompted studies on multiple mechanisms including genetic predisposition, brain biochemistry, immunological responses, and microbial insult. In particular, Lyme disease is often associated with...
14.
Davalieva K, Kiprijanovska S, Dimovski A, Rosoklija G, Dwork A
J Proteomics
. 2021 Jan;
235:104117.
PMID: 33453434
The proteomics of formalin-fixed, paraffin-embedded (FFPE) samples has advanced significantly during the last two decades, but there are many protocols and few studies comparing them directly. There is no consensus...
15.
Hartstone W, Brown M, Kelly G, Tate W, Kuo S, Dwork A, et al.
Mov Disord
. 2020 Dec;
36(4):995-999.
PMID: 33258511
Background: Essential tremor involves the cerebellum, yet quantitative analysis of dentate nucleus neurons has not been conducted. Objectives: To quantitatively compare neuronal density or neuronal number in the dentate nucleus...
16.
Zhu Y, Dwork A, Trifilieff P, Javitch J
Curr Protoc Neurosci
. 2020 Jan;
91(1):e86.
PMID: 31943888
Combining immunological and molecular biological methods, the antibody-based proximity ligation assay (PLA) has been used for more than a decade to detect and quantify protein-protein interactions, protein modification, and protein...
17.
Zhu Y, Meszaros J, Walle R, Fan R, Sun Z, Dwork A, et al.
Biotechniques
. 2019 Dec;
68(3):122-129.
PMID: 31859535
Despite the controversy regarding the existence and physiological relevance of class A G protein-coupled receptor dimerization, there is substantial evidence for functional interactions between the dopamine D2 receptor (D2R) and...
18.
Janjic P, Petrovski K, Dolgoski B, Smiley J, Zdravkovski P, Pavlovski G, et al.
J Neurosci Methods
. 2019 Aug;
326:108373.
PMID: 31377177
Background: Standard segmentation of high-contrast electron micrographs (EM) identifies myelin accurately but does not translate easily into measurements of individual axons and their myelin, even in cross-sections of parallel fibers....
19.
Underwood M, Bakalian M, Dwork A, Min E, Mann J, Arango V
J Psychiatr Brain Sci
. 2019 Jun;
4(2).
PMID: 31245628
Alcohol increases inhibitory neurotransmission, an effect mediated through GABA receptors. With chronic alcohol exposure, the inhibitory effects diminish. Glutamic acid decarboxylase (GAD) catalyzes glutamate in the synthesis of GABA. We...
20.
Boldrini M, Galfalvy H, Dwork A, Rosoklija G, Trencevska-Ivanovska I, Pavlovski G, et al.
Biol Psychiatry
. 2019 Mar;
85(10):850-862.
PMID: 30819514
Background: Early life adversity (ELA) increases major depressive disorder (MDD) and suicide risk and potentially affects dentate gyrus (DG) plasticity. We reported smaller DG and fewer granular neurons (GNs) in...