Andrew J Deans
Overview
Explore the profile of Andrew J Deans including associated specialties, affiliations and a list of published articles.
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Articles
54
Citations
2357
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Recent Articles
1.
Abbouche L, Murphy V, Gao J, van Twest S, Sobinoff A, Auweiler K, et al.
Nucleic Acids Res
. 2024 Aug;
52(18):11029-11044.
PMID: 39189453
FANCM is a DNA repair protein that recognizes stalled replication forks, and recruits downstream repair factors. FANCM activity is also essential for the survival of cancer cells that utilize the...
2.
Abbouche L, Bythell-Douglas R, Deans A
DNA Repair (Amst)
. 2024 Jun;
140:103701.
PMID: 38878565
FANCM is a multifunctional DNA repair enzyme that acts as a sensor and coordinator of replication stress responses, especially interstrand crosslink (ICL) repair mediated by the Fanconi anaemia (FA) pathway....
3.
Ngo L, Bert A, Dredge B, Williams T, Murphy V, Li W, et al.
Nature
. 2024 Mar;
627(8005):E12.
PMID: 38480896
No abstract available.
4.
Yang S, Nelson C, Wells J, Fernando M, Lu R, Allen J, et al.
Nat Commun
. 2024 Mar;
15(1):2210.
PMID: 38472229
The ATR-CHK1 DNA damage response pathway becomes activated by the exposure of RPA-coated single-stranded DNA (ssDNA) that forms as an intermediate during DNA damage and repair, and as a part...
5.
Ngo L, Bert A, Dredge B, Williams T, Murphy V, Li W, et al.
Nature
. 2024 Feb;
627(8002):212-220.
PMID: 38355801
Circular RNAs (circRNAs), which are increasingly being implicated in a variety of functions in normal and cancerous cells, are formed by back-splicing of precursor mRNAs in the nucleus. circRNAs are...
6.
Tsui V, Lyu R, Novakovic S, Stringer J, Dunleavy J, Granger E, et al.
Cell Genom
. 2023 Aug;
3(8):100349.
PMID: 37601968
Meiotic crossovers are required for accurate chromosome segregation and producing new allelic combinations. Meiotic crossover numbers are tightly regulated within a narrow range, despite an excess of initiating DNA double-strand...
7.
Hodson C, van Twest S, Dylewska M, ORourke J, Tan W, Murphy V, et al.
Cell Rep
. 2022 Dec;
41(10):111749.
PMID: 36476850
Co-transcriptional R loops arise from stalling of RNA polymerase, leading to the formation of stable DNA:RNA hybrids. Unresolved R loops promote genome instability but are counteracted by helicases and nucleases....
8.
Hodson C, Low J, van Twest S, Jones S, Swuec P, Murphy V, et al.
Proc Natl Acad Sci U S A
. 2022 Feb;
119(6).
PMID: 35115399
The RecQ-like helicase BLM cooperates with topoisomerase IIIα, RMI1, and RMI2 in a heterotetrameric complex (the "Bloom syndrome complex") for dissolution of double Holliday junctions, key intermediates in homologous recombination....
9.
Peterlongo P, Figlioli G, Deans A, Couch F
NPJ Breast Cancer
. 2021 Sep;
7(1):130.
PMID: 34584094
No abstract available.
10.
Samaraweera S, Wang P, Li K, Casolari D, Feng J, Pinese M, et al.
Blood
. 2021 Sep;
138(22):2293-2298.
PMID: 34521114
No abstract available.