Andrew J Conley
Overview
Explore the profile of Andrew J Conley including associated specialties, affiliations and a list of published articles.
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16
Citations
398
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Recent Articles
1.
Bardeen C, Garcia R, Toon O, Conley A
Proc Natl Acad Sci U S A
. 2017 Aug;
114(36):E7415-E7424.
PMID: 28827324
Climate simulations that consider injection into the atmosphere of 15,000 Tg of soot, the amount estimated to be present at the Cretaceous-Paleogene boundary, produce what might have been one of...
2.
Reuter L, Conley A, Joensuu J
Methods Mol Biol
. 2015 Nov;
1385:189-97.
PMID: 26614291
Fusion to fungal hydrophobins has proven to be a useful tool to enhance accumulation and recovery of recombinant proteins in plants. Aqueous two-phase separation (ATPS) is an attractive system to...
3.
Saberianfar R, Joensuu J, Conley A, Menassa R
Plant Biotechnol J
. 2015 Feb;
13(7):927-37.
PMID: 25640969
Protein bodies (PBs) are endoplasmic reticulum (ER) derived organelles originally found in seeds whose function is to accumulate seed storage proteins. It has been shown that PB formation is not...
4.
DiCarlo J, Conley A, Penttila M, Jantti J, Wang H, Church G
ACS Synth Biol
. 2013 Oct;
2(12):741-9.
PMID: 24160921
High-frequency oligonucleotide-directed recombination engineering (recombineering) has enabled rapid modification of several prokaryotic genomes to date. Here, we present a method for oligonucleotide-mediated recombineering in the model eukaryote and industrial production...
5.
Joensuu J, Conley A, Linder M, Menassa R
Methods Mol Biol
. 2011 Dec;
824:527-34.
PMID: 22160918
Two main hurdles hinder the widespread acceptance of plants as a preferred protein expression platform: low accumulation levels and expensive chromatographic purification methods. Fusion of proteins of interest to fungal...
6.
Conley A, Joensuu J, Richman A, Menassa R
Plant Biotechnol J
. 2011 Feb;
9(4):419-33.
PMID: 21338467
For the past two decades, therapeutic and industrially important proteins have been expressed in plants with varying levels of success. The two major challenges hindering the economical production of plant-made...
7.
Ahmad A, Pereira E, Conley A, Richman A, Menassa R
Recent Pat Biotechnol
. 2010 Dec;
4(3):242-59.
PMID: 21171961
Until recently, low accumulation levels have been the major bottleneck for plant-made recombinant protein production. However, several breakthroughs have been described in the past few years allowing for very high...
8.
Conley A, Zhu H, Le L, Jevnikar A, Lee B, Brandle J, et al.
Plant Biotechnol J
. 2010 Nov;
9(4):434-44.
PMID: 21040385
Although many different crop species have been used to produce a wide range of vaccines, antibodies, biopharmaceuticals and industrial enzymes, tobacco has the most established history for the production of...
9.
Ahmad A, Pereira E, Conley A, Richman A, Menassa R
Recent Pat Biotechnol
. 2010 Apr;
PMID: 20423324
Until recently, low accumulation levels have been the major bottleneck for plant-made recombinant protein production. However, several breakthroughs have been described in the past few years allowing for very high...
10.
Joensuu J, Conley A, Lienemann M, Brandle J, Linder M, Menassa R
Plant Physiol
. 2009 Dec;
152(2):622-33.
PMID: 20018596
Insufficient accumulation levels of recombinant proteins in plants and the lack of efficient purification methods for recovering these valuable proteins have hindered the development of plant biotechnology applications. Hydrophobins are...