Andrew I Webb
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Explore the profile of Andrew I Webb including associated specialties, affiliations and a list of published articles.
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88
Citations
3887
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Recent Articles
1.
Improved drug target deconvolution with PISA-DIA using an extended, overlapping temperature gradient
Emery-Corbin S, Yousef J, Adhikari S, Sumardy F, Nhu D, van Delft M, et al.
Proteomics
. 2024 May;
24(16):e2300644.
PMID: 38766901
Thermal proteome profiling (TPP) is a powerful tool for drug target deconvolution. Recently, data-independent acquisition mass spectrometry (DIA-MS) approaches have demonstrated significant improvements to depth and missingness in proteome data,...
2.
Fietz D, Sgaier R, ODonnell L, Stanton P, Dagley L, Webb A, et al.
Front Endocrinol (Lausanne)
. 2024 Apr;
15:1327800.
PMID: 38654926
Introduction: Azoospermia, characterized by an absence of sperm in the ejaculate, represents the most severe form of male infertility. While surgical sperm retrieval in obstructive azoospermia (OA) is successful in...
3.
Identification of Serum Biomarkers to Monitor Therapeutic Response in Intestinal-Type Gastric Cancer
Dagley L, Yousef J, Preaudet A, Loving A, Webb A, Ernst M, et al.
Int J Mol Sci
. 2024 Mar;
25(6).
PMID: 38542101
There are a limited number of clinically useful serum biomarkers to predict tumor onset or treatment response in gastric cancer (GC). For this reason, we explored the serum proteome of...
4.
Nicolson S, Manning J, Lim Y, Jiang X, Kolze E, Dayan S, et al.
Commun Biol
. 2024 Feb;
7(1):183.
PMID: 38360932
Autophagy, the process of elimination of cellular components by lysosomal degradation, is essential for animal development and homeostasis. Using the autophagy-dependent Drosophila larval midgut degradation model we identified an autophagy...
5.
Delconte R, Kolesnik T, Dagley L, Rautela J, Shi W, Putz E, et al.
Nat Immunol
. 2023 Dec;
25(2):371-372.
PMID: 38087084
No abstract available.
6.
Pandey K, Wang S, Mifsud N, Faridi P, Davenport A, Webb A, et al.
Front Oncol
. 2023 Aug;
13:1192448.
PMID: 37637064
Introduction: Diffuse intrinsic pontine glioma (DIPG), recently reclassified as a subtype of diffuse midline glioma, is a highly aggressive brainstem tumor affecting children and young adults, with no cure and...
7.
Hediyeh-Zadeh S, Webb A, Davis M
Mol Cell Proteomics
. 2023 Apr;
22(8):100558.
PMID: 37105364
Mass spectrometry (MS) enables high-throughput identification and quantification of proteins in complex biological samples and can provide insights into the global function of biological systems. Label-free quantification is cost-effective and...
8.
Wilding-McBride D, Webb A
PLoS One
. 2022 Nov;
17(11):e0277122.
PMID: 36449500
Identification of peptides by analysis of data acquired by the two established methods for bottom-up proteomics, DDA and DIA, relies heavily on the fragment spectra. In DDA, peptide features detected...
9.
Wilding-McBride D, Dagley L, Spall S, Infusini G, Webb A
PLoS One
. 2022 Jul;
17(7):e0271025.
PMID: 35797390
For bottom-up proteomic analysis, the goal of analytical pipelines that process the raw output of mass spectrometers is to detect, characterise, identify, and quantify peptides. The initial steps of detecting...
10.
Liu L, Sandow J, Leslie Pedrioli D, Samson A, Silke N, Kratina T, et al.
Sci Adv
. 2022 May;
8(19):eabh2332.
PMID: 35544574
Tumor necrosis factor (TNF) is a key component of the innate immune response. Upon binding to its receptor, TNFR1, it promotes production of other cytokines via a membrane-bound complex 1...