Andrew G Soerens
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Explore the profile of Andrew G Soerens including associated specialties, affiliations and a list of published articles.
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14
Citations
1586
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Recent Articles
1.
Scott M, Steier Z, Pierson M, Stolley J, OFlanagan S, Soerens A, et al.
Immunity
. 2024 Dec;
58(1):162-181.e10.
PMID: 39708817
Tissue-resident memory CD8 T (Trm) cells control infections and cancer and are defined by their lack of recirculation. Because migration is difficult to assess, residence is usually inferred by putative...
2.
Mi T, Soerens A, Alli S, Kang T, Vasandan A, Wang Z, et al.
Nat Aging
. 2024 Jun;
4(8):1053-1063.
PMID: 38867059
Chronological aging correlates with epigenetic modifications at specific loci, calibrated to species lifespan. Such 'epigenetic clocks' appear conserved among mammals, but whether they are cell autonomous and restricted by maximal...
3.
Stolley J, Scott M, Joag V, Dale A, Johnston T, Saavedra F, et al.
J Exp Med
. 2023 Apr;
220(7).
PMID: 37097449
The oral mucosa is a frontline for microbial exposure and juxtaposes several unique tissues and mechanical structures. Based on parabiotic surgery of mice receiving systemic viral infections or co-housing with...
4.
Soerens A, Kunzli M, Quarnstrom C, Scott M, Swanson L, Locquiao J, et al.
Nature
. 2023 Jan;
614(7949):762-766.
PMID: 36653453
Differentiated somatic mammalian cells putatively exhibit species-specific division limits that impede cancer but may constrain lifespans. To provide immunity, transiently stimulated CD8 T cells undergo unusually rapid bursts of numerous...
5.
Kunzli M, OFlanagan S, LaRue M, Talukder P, Dileepan T, Stolley J, et al.
Sci Immunol
. 2022 Dec;
7(78):eadd3075.
PMID: 36459542
Respiratory tract resident memory T cells (T), typically generated by local vaccination or infection, can accelerate control of pulmonary infections that evade neutralizing antibody. It is unknown whether mRNA vaccination...
6.
Matchett W, Joag V, Stolley J, Shepherd F, Quarnstrom C, Mickelson C, et al.
J Immunol
. 2021 Jul;
207(2):376-379.
PMID: 34193597
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the COVID-19 pandemic. Neutralizing Abs target the receptor binding domain of the spike (S) protein, a focus of successful vaccine...
7.
Matchett W, Joag V, Stolley J, Shepherd F, Quarnstrom C, Mickelson C, et al.
bioRxiv
. 2021 May;
PMID: 33948591
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the COVID-19 pandemic. Neutralizing antibodies target the receptor binding domain of the spike (S) protein, a focus of successful vaccine...
8.
Joag V, Wijeyesinghe S, Stolley J, Quarnstrom C, Dileepan T, Soerens A, et al.
J Immunol
. 2021 Jan;
206(5):931-935.
PMID: 33441437
The magnitude of SARS-CoV-2-specific T cell responses correlates inversely with human disease severity, suggesting T cell involvement in primary control. Whereas many COVID-19 vaccines focus on establishing humoral immunity to...
9.
Stolley J, Johnston T, Soerens A, Beura L, Rosato P, Joag V, et al.
J Exp Med
. 2020 Jun;
217(8).
PMID: 32568362
Numerous observations indicate that resident memory T cells (TRM) undergo unusually rapid attrition within the lung. Here we demonstrate that contraction of lung CD8+ T cell responses after influenza infection...
10.
Masopust D, Soerens A
Annu Rev Immunol
. 2019 Feb;
37:521-546.
PMID: 30726153
Resident memory T (Trm) cells stably occupy tissues and cannot be sampled in superficial venous blood. Trm cells are heterogeneous but collectively constitute the most abundant memory T cell subset....