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Andrew Futreal

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Articles 109
Citations 5761
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Recent Articles
1.
Perelli L, Zhang L, Mangiameli S, Giannese F, Mahadevan K, Peng F, et al.
Nature . 2025 Mar; PMID: 40044861
Mesenchymal plasticity has been extensively described in advanced epithelial cancers; however, its functional role in malignant progression is controversial. The function of epithelial-to-mesenchymal transition (EMT) and cell plasticity in tumour...
2.
Goswami S, Gao J, Basu S, Shapiro D, Karam J, Tidwell R, et al.
Nat Commun . 2025 Feb; 16(1):1846. PMID: 39984485
Surgical removal of primary tumors reverses tumor-mediated immune suppression in pre-clinical models with metastatic disease. However, how cytoreductive surgery in the metastatic setting modulates the immune responses in patients, especially...
3.
Bayraktar R, Tang Y, Dragomir M, Ivan C, Peng X, Fabris L, et al.
Sci Adv . 2025 Feb; 11(8):eado2830. PMID: 39970212
The mutational landscape of phylogenetically ultraconserved elements (UCEs), especially those in noncoding DNAs (ncUCEs), and their functional relevance in cancers remain poorly characterized. Here, we perform a systematic analysis of...
4.
Goswami S, Gao J, Basu S, Shapiro D, Karam J, Tidwell R, et al.
Res Sq . 2024 Nov; PMID: 39606482
Surgical removal of primary tumors was shown to reverse tumor-mediated immune suppression in pre-clinical models with metastatic disease. However, how cytoreductive surgery in the metastatic setting modulates the immune responses...
5.
Yoshida-Court K, Karpinets T, Mitra A, Solley T, Dorta-Estremera S, Sims T, et al.
PLoS One . 2024 Nov; 19(11):e0314643. PMID: 39576772
[This corrects the article DOI: 10.1371/journal.pone.0279590.].
6.
Wang X, Zhao L, Song X, Wu X, Krishnamurthy S, Semba T, et al.
NPJ Precis Oncol . 2024 Nov; 8(1):265. PMID: 39558017
Triple-negative inflammatory breast cancer (TN-IBC) is the most aggressive type of breast cancer, yet its defining genomic, molecular, and immunological features remain largely unknown. In this study, we performed the...
7.
Zhang S, Jiang V, Han G, Hao D, Lian J, Liu Y, et al.
Nat Commun . 2024 Oct; 15(1):8668. PMID: 39375332
No abstract available.
8.
Jiang J, Liu Y, Qin J, Chen J, Wu J, Pizzi M, et al.
Nat Commun . 2024 Aug; 15(1):7312. PMID: 39181865
Recent advances in spatial transcriptomics (ST) techniques provide valuable insights into cellular interactions within the tumor microenvironment (TME). However, most analytical tools lack consideration of histological features and rely on...
9.
Cheng X, Dai E, Wu J, Flores N, Chu Y, Wang R, et al.
Gastroenterology . 2024 Aug; 167(7):1345-1357. PMID: 39097198
Background & Aims: Metastases from gastric adenocarcinoma (GAC) lead to high morbidity and mortality. Developing innovative and effective therapies requires a comprehensive understanding of the tumor and immune biology of...
10.
Kim S, Chu Y, Misoi M, Suarez-Almazor M, Tayar J, Lu H, et al.
Nat Commun . 2024 Jul; 15(1):5621. PMID: 38965214
No abstract available.