Andrew D Hamilton
Overview
Explore the profile of Andrew D Hamilton including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
177
Citations
3880
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Maity D, Oh Y, Gremer L, Hoyer W, Magzoub M, Hamilton A
Chemistry
. 2022 Jun;
28(38):e202201698.
PMID: 35701098
Invited for the cover of this issue is the group of Prof. Hamilton at New York University. The image depicts how cucurbit[7]uril inhibits islet amyloid polypeptide self-assembly that rescues rat...
2.
Maity D, Oh Y, Gremer L, Hoyer W, Magzoub M, Hamilton A
Chemistry
. 2022 May;
28(38):e202200456.
PMID: 35532096
Two "hot segments" within an islet amyloid polypeptide are responsible for its self-assembly, which in turn is linked to the decline of β-cells in type 2 diabetes (T2D). A readily...
3.
Bavinton C, Sternke-Hoffmann R, Yamashita T, Knipe P, Hamilton A, Luo J, et al.
Chem Commun (Camb)
. 2022 Apr;
58(33):5132-5135.
PMID: 35380562
Misfolding of the human protein α-synuclein results in toxic fibrils and the aggregation of Lewy bodies, which are a hallmark of Parkinson's disease in brain tissue. Here we disclose a...
4.
Busschaert N, Maity D, Samanta P, English N, Hamilton A
Chembiochem
. 2022 Jan;
23(6):e202100670.
PMID: 34985829
The thrombin binding aptamer (TBA) is a 15-mer DNA oligonucleotide (5'-GGT TGG TGT GGT TGG-3'), that can form a stable intramolecular antiparallel chair-like G-quadruplex structure. This aptamer shows anticoagulant properties...
5.
Maity D, Hamilton A
Chem Commun (Camb)
. 2021 Sep;
57(73):9192-9195.
PMID: 34519293
A metal-free and achiral tri-pyridylamide foldamer, DM 11, containing a critical naphthalimide side chain self-assembles in a left-handed helical manner in the presence of chiral adenosine phosphates, under physiological conditions....
6.
Maity D, Kumar S, AlHussein R, Gremer L, Howarth M, Karpauskaite L, et al.
RSC Chem Biol
. 2021 Aug;
1(4):225-232.
PMID: 34458762
Membrane-catalysed misfolding of islet amyloid polypeptide is associated with the death of β-cells in type II diabetes (T2D). Most active compounds so far reported require high doses for inhibition of...
7.
Palanikumar L, Karpauskaite L, Al-Sayegh M, Chehade I, Alam M, Hassan S, et al.
Nat Commun
. 2021 Jun;
12(1):3962.
PMID: 34172723
Missense mutations in p53 are severely deleterious and occur in over 50% of all human cancers. The majority of these mutations are located in the inherently unstable DNA-binding domain (DBD),...
8.
Maity D, Howarth M, Vogel M, Magzoub M, Hamilton A
J Am Chem Soc
. 2021 Feb;
143(8):3086-3093.
PMID: 33600171
An interruption in Aβ homeostasis leads to the deposit of neurotoxic amyloid plaques and is associated with Alzheimer's disease. A supramolecular strategy based on the assembly of peptidomimetic agents into...
9.
Peacock H, Troeira Henriques S, Benfield A, Elliott A, Luo J, Luccarelli J, et al.
ChemMedChem
. 2020 Aug;
15(20):1932-1939.
PMID: 32754982
Mimics of natural antimicrobial peptides are promising compounds to fight the rising threat of multi-drug resistant bacteria. Here we report the design, synthesis and conformational analysis of a new class...
10.
Meisel J, Hu C, Hamilton A
Org Lett
. 2019 Sep;
21(19):7763-7767.
PMID: 31535554
Macrocyclic hosts have long been the workhorses of molecular recognition. Despite the widespread use of container-shaped molecules as synthetic receptors, an efficient preparation of cavitands bearing multiple functional groups has...