Andrew C Wakeham
Overview
Explore the profile of Andrew C Wakeham including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
227
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0
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Recent Articles
1.
Nechanitzky R, Ramachandran P, Nechanitzky D, Li W, Wakeham A, Haight J, et al.
Cell Death Differ
. 2024 Feb;
31(3):265-279.
PMID: 38383888
PirB is an inhibitory cell surface receptor particularly prominent on myeloid cells. PirB curtails the phenotypes of activated macrophages during inflammation or tumorigenesis, but its functions in macrophage homeostasis are...
2.
Zheng C, Snow B, Elia A, Nechanitzky R, Dominguez-Brauer C, Liu S, et al.
Nat Cancer
. 2023 Aug;
4(10):1437-1454.
PMID: 37640929
Cholinergic nerves are involved in tumor progression and dissemination. In contrast to other visceral tissues, cholinergic innervation in the hepatic parenchyma is poorly detected. It remains unclear whether there is...
3.
Nechanitzky R, Nechanitzky D, Ramachandran P, Duncan G, Zheng C, Gobl C, et al.
Cell Death Differ
. 2022 Dec;
30(2):407-416.
PMID: 36528755
Experimental autoimmune encephalomyelitis (EAE) is a mouse model of multiple sclerosis (MS) in which Th17 cells have a crucial but unclear function. Here we show that choline acetyltransferase (ChAT), which...
4.
Gui J, Zahedi F, Ortiz A, Cho C, Katlinski K, Alicea-Torres K, et al.
Nat Cancer
. 2021 Jun;
1(6):603-619.
PMID: 34124690
Primary tumor-derived factors (TDFs) act upon normal cells to generate a pre-metastatic niche, which promotes colonization of target organs by disseminated malignant cells. Here we report that TDFs-induced activation of...
5.
Cox M, Duncan G, Lin G, Steinberg B, Yu L, Brenner D, et al.
Science
. 2019 Feb;
363(6427):639-644.
PMID: 30733420
Although widely studied as a neurotransmitter, T cell-derived acetylcholine (ACh) has recently been reported to play an important role in regulating immunity. However, the role of lymphocyte-derived ACh in viral...
6.
McIlwain D, Pan Q, Reilly P, Elia A, McCracken S, Wakeham A, et al.
Proc Natl Acad Sci U S A
. 2010 Jun;
107(27):12186-91.
PMID: 20566848
Smg1 is a PI3K-related kinase (PIKK) associated with multiple cellular functions, including DNA damage responses, telomere maintenance, and nonsense-mediated mRNA decay (NMD). NMD degrades transcripts that harbor premature termination codons...
7.
Hara H, Takeda A, Takeuchi M, Wakeham A, Itie A, Sasaki M, et al.
J Immunol
. 2002 Feb;
168(5):2288-95.
PMID: 11859117
Negative selection is a process to delete potentially autoreactive clones in developing thymocytes. Programmed cell death or apoptosis is thought to play an important role in this selection process. In...