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Andrew C Robinson

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Articles 61
Citations 1044
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Recent Articles
1.
Iwata N, Tsubuki S, Sekiguchi M, Watanabe-Iwata K, Matsuba Y, Kamano N, et al.
Life Sci Alliance . 2024 Sep; 7(12). PMID: 39348937
The amyloid β peptide (Aβ), starting with pyroglutamate (pE) at position 3 and ending at position 42 (Aβ3pE-42), predominantly accumulates in the brains of Alzheimer's disease. Consistently, donanemab, a therapeutic...
2.
Didikoglu A, Guler E, Turk H, Can K, Erim A, Payton A, et al.
J Affect Disord . 2024 Aug; 366:379-385. PMID: 39216641
Background: Depression among older adults is a global concern, contributing to disability and overall illness burden. Understanding its trajectory, associated risk factors, and implications for mortality is essential for effective...
3.
Bhattacharjee S, Scotton W, Djoukhadar I, Davidson Y, Minshull J, Robinson A, et al.
Mov Disord Clin Pract . 2024 Jun; 11(8):1025-1029. PMID: 38826096
Background: Corticobasal syndrome is a clinical diagnosis and common pathological causes are corticobasal degeneration, progressive supranuclear palsy and Alzheimer's disease. Objectives: We would like to highlight a rare but important...
4.
Stepan J, Heinz D, Dethloff F, Wiechmann S, Martinelli S, Hafner K, et al.
Sci Signal . 2024 Apr; 17(834):eadj6603. PMID: 38687825
The localization, number, and function of postsynaptic AMPA-type glutamate receptors (AMPARs) are crucial for synaptic plasticity, a cellular correlate for learning and memory. The Hippo pathway member WWC1 is an...
5.
Valentino R, Scotton W, Roemer S, Lashley T, Heckman M, Shoai M, et al.
Lancet Neurol . 2024 Apr; 23(5):487-499. PMID: 38631765
Background: Pick's disease is a rare and predominantly sporadic form of frontotemporal dementia that is classified as a primary tauopathy. Pick's disease is pathologically defined by the presence in the...
6.
Robinson A, Bin Rizwan T, Davidson Y, Minshull J, Tinkler P, Payton A, et al.
J Alzheimers Dis . 2024 Mar; 98(4):1457-1466. PMID: 38552117
Background: While mid-life hypertension represents a risk factor for the development of Alzheimer's disease (AD), the risk after the age of 65 is less certain. Establishing relationships between late life...
7.
Hartmann J, Bajaj T, Otten J, Klengel C, Ebert T, Gellner A, et al.
Nat Commun . 2024 Mar; 15(1):2635. PMID: 38528004
High levels of proinflammatory cytokines induce neurotoxicity and catalyze inflammation-driven neurodegeneration, but the specific release mechanisms from microglia remain elusive. Here we show that secretory autophagy (SA), a non-lytic modality...
8.
Minshull J, Davidson Y, Roncaroli F, Robinson A
Brain Pathol . 2024 Jan; 34(5):e13243. PMID: 38270230
Formalin-fixed paraffin-embedded (FFPE) brain tissue held in tissue banks constitutes a valuable research resource, especially when associated with clinical annotations and longitudinal psychometric testing. Apolipoprotein-E (APOE) genotyping is important to...
9.
Kobylecki C, Thompson J, Robinson A, Roncaroli F, Snowden J, Mann D
Brain Pathol . 2023 Nov; 34(4):e13219. PMID: 37927160
A 70-year-old man presented to the clinic with impairment of visual memory and marked predominantly right sided mesial temporal lobe atrophy on imaging. He died 6 years following symptom onset...
10.
Tarutani A, Kametani F, Tahira M, Saito Y, Yoshida M, Robinson A, et al.
Brain . 2023 Oct; 146(12):4988-4999. PMID: 37904205
Pathological tau accumulates in the brain in tauopathies such as Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration, and forms amyloid-like filaments incorporating various post-translational modifications (PTMs). Cryo-electron...