Andrew C Penn
Overview
Explore the profile of Andrew C Penn including associated specialties, affiliations and a list of published articles.
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14
Citations
596
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Recent Articles
1.
Winchester G, Steele O, Liu S, Maia Chagas A, Aziz W, Penn A
Front Neuroinform
. 2024 Sep;
18:1427642.
PMID: 39345285
Detection and analysis of spontaneous synaptic events is an extremely common task in many neuroscience research labs. Various algorithms and tools have been developed over the years to improve the...
2.
Elmasri M, Lotti J, Aziz W, Steele O, Karachaliou E, Sakimura K, et al.
Brain Sci
. 2022 Jun;
12(6).
PMID: 35741674
mutations are rare but often associated with patients having severe neurodevelopmental disorders with varying range of symptoms such as intellectual disability, developmental delay and epilepsy. Patient symptoms likely arise from...
3.
Hafner A, Penn A, Grillo-Bosch D, Retailleau N, Poujol C, Philippat A, et al.
Neuron
. 2015 Apr;
86(2):475-89.
PMID: 25843401
PSD-95 is a prominent organizer of the postsynaptic density (PSD) that can present a filamentous orientation perpendicular to the plasma membrane. Interactions between PSD-95 and transmembrane proteins might be particularly...
4.
Constals A, Penn A, Compans B, Toulme E, Phillipat A, Marais S, et al.
Neuron
. 2015 Feb;
85(4):787-803.
PMID: 25661182
Short-term plasticity of AMPAR currents during high-frequency stimulation depends not only on presynaptic transmitter release and postsynaptic AMPAR recovery from desensitization, but also on fast AMPAR diffusion. How AMPAR diffusion...
5.
Penn A, Balik A, Greger I
Front Neurosci
. 2013 Apr;
7:61.
PMID: 23616744
The fine control of molecules mediating communication in the nervous system is key to adjusting neuronal signaling during development and in maintaining the stability of established networks in the face...
6.
Penn A, Balik A, Greger I
Nucleic Acids Res
. 2012 Nov;
41(2):1113-23.
PMID: 23172291
Adenosine-to-Inosine (A-to-I) RNA editing is a post-transcriptional mechanism, evolved to diversify the transcriptome in metazoa. In addition to wide-spread editing in non-coding regions protein recoding by RNA editing allows for...
7.
Balik A, Penn A, Nemoda Z, Greger I
Nucleic Acids Res
. 2012 Nov;
41(2):1124-34.
PMID: 23172290
RNA editing by adensosine deaminases is a widespread mechanism to alter genetic information in metazoa. In addition to modifications in non-coding regions, editing contributes to diversification of protein function, in...
8.
Penn A, Balik A, Wozny C, Cais O, Greger I
Neuron
. 2012 Nov;
76(3):503-10.
PMID: 23141062
The AMPA-type glutamate receptor (AMPAR) subunit composition shapes synaptic transmission and varies throughout development and in response to different input patterns. Here, we show that chronic activity deprivation gives rise...
9.
Sukumaran M, Penn A, Greger I
Adv Exp Med Biol
. 2012 Feb;
970:241-64.
PMID: 22351059
Glutamate-gated ion channels (iGluRs) predominantly operate as heterotetramers to mediate excitatory neurotransmission at glutamatergic synapses. The subunit composition of the receptors determines their targeting to synaptic sites and signalling properties...
10.
Rossmann M, Sukumaran M, Penn A, Veprintsev D, Babu M, Greger I
EMBO J
. 2011 Feb;
30(5):959-71.
PMID: 21317873
The assembly of AMPA-type glutamate receptors (AMPARs) into distinct ion channel tetramers ultimately governs the nature of information transfer at excitatory synapses. How cells regulate the formation of diverse homo-...