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Andrew C Payne

Explore the profile of Andrew C Payne including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 279
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Recent Articles
1.
Labade A, Chiang Z, Comenho C, Reginato P, Payne A, Earl A, et al.
bioRxiv . 2024 Oct; PMID: 39386718
Microscopy and genomics are both used to characterize cell function, but approaches to connect the two types of information are lacking, particularly at subnuclear resolution. While emerging multiplexed imaging methods...
2.
Alon S, Goodwin D, Sinha A, Wassie A, Chen F, Daugharthy E, et al.
Science . 2021 Jan; 371(6528). PMID: 33509999
Methods for highly multiplexed RNA imaging are limited in spatial resolution and thus in their ability to localize transcripts to nanoscale and subcellular compartments. We adapt expansion microscopy, which physically...
3.
Payne A, Chiang Z, Reginato P, Mangiameli S, Murray E, Yao C, et al.
Science . 2021 Jan; 371(6532). PMID: 33384301
Understanding genome organization requires integration of DNA sequence and three-dimensional spatial context; however, existing genome-wide methods lack either base pair sequence resolution or direct spatial localization. Here, we describe in...
4.
Haagensen E, Thomas H, Schmalix W, Payne A, Kevorkian L, Allen R, et al.
Cancer Chemother Pharmacol . 2016 Nov; 78(6):1269-1281. PMID: 27837257
Purpose: Tumours frequently have defects in multiple oncogenic pathways, e.g. MAPK and PI3K signalling pathways, and combinations of targeted therapies may be required for optimal activity. This study evaluated the...
5.
Payne A, Andregg M, Kemmish K, Hamalainen M, Bowell C, Bleloch A, et al.
PLoS One . 2013 Aug; 8(7):e69058. PMID: 23935923
We present "molecular threading", a surface independent tip-based method for stretching and depositing single and double-stranded DNA molecules. DNA is stretched into air at a liquid-air interface, and can be...