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Andrew C McShan

Explore the profile of Andrew C McShan including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 501
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Recent Articles
1.
Frooman M, Choi K, Kahn M, Yang L, Cunningham A, RisCassi J, et al.
Sci Rep . 2025 Mar; 15(1):8614. PMID: 40074802
Human Leukocyte Antigens (HLA) are immunoreceptors that present peptide antigens at the cell surface to T cells as a primary mechanism of immune surveillance. Malaria, a disease associated with the...
2.
Yang L, Ping K, Luo Y, McShan A
Commun Chem . 2024 Dec; 7(1):288. PMID: 39633021
Lipid-protein interactions are crucial for virtually all biological processes in living cells. However, existing structural databases focusing on these interactions are limited to integral membrane proteins. A systematic understanding of...
3.
Lisanza S, Gershon J, Tipps S, Sims J, Arnoldt L, Hendel S, et al.
Nat Biotechnol . 2024 Oct; PMID: 39375454
No abstract available.
4.
Lisanza S, Gershon J, Tipps S, Sims J, Arnoldt L, Hendel S, et al.
Nat Biotechnol . 2024 Sep; PMID: 39322764
Protein denoising diffusion probabilistic models are used for the de novo generation of protein backbones but are limited in their ability to guide generation of proteins with sequence-specific attributes and...
5.
Srinivasan S, Zhu C, McShan A
Front Immunol . 2024 Sep; 15:1412513. PMID: 39253084
Expressed on the surface of CD8 T cells, the CD8 co-receptor is a key component of the T cells that contributes to antigen recognition, immune cell maturation, and immune cell...
6.
Dodd-O J, Roy A, Siddiqui Z, Jafari R, Coppola F, Ramasamy S, et al.
Nat Commun . 2024 Aug; 15(1):7412. PMID: 39198458
No abstract available.
7.
Zhong W, Olugbami J, Rathakrishnan P, Mohanty I, Moore S, Garg N, et al.
J Org Chem . 2024 Aug; 89(17):12748-12752. PMID: 39189383
We describe the discovery and structure of an undecapeptide natural product from a marine sponge, termed halichondamide A, that is morphed into a fused bicyclic ring topology via two disulfide...
8.
Agarwal V, McShan A
Nat Chem Biol . 2024 Jun; 20(8):950-959. PMID: 38907110
Artificial intelligence-driven advances in protein structure prediction in recent years have raised the question: has the protein structure-prediction problem been solved? Here, with a focus on nonglobular proteins, we highlight...
9.
Robang A, Roy A, Dodd-O J, He D, Le J, McShan A, et al.
Biomacromolecules . 2024 Feb; 25(3):1429-1438. PMID: 38408372
We applied solid- and solution-state nuclear magnetic resonance spectroscopy to examine the structure of multidomain peptides composed of self-assembling β-sheet domains linked to bioactive domains. Bioactive domains can be selected...
10.
Dodd-O J, Roy A, Siddiqui Z, Jafari R, Coppola F, Ramasamy S, et al.
Nat Commun . 2024 Feb; 15(1):1505. PMID: 38374216
No abstract available.