Andrew B Herr
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Explore the profile of Andrew B Herr including associated specialties, affiliations and a list of published articles.
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95
Citations
2776
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Recent Articles
1.
Yarawsky A, Herr A
Biophys J
. 2024 Dec;
124(2):363-378.
PMID: 39668565
The accumulation-associated protein (Aap) is the primary determinant of Staphylococcus epidermidis device-related infections. The B-repeat superdomain is responsible for intercellular adhesion that leads to the development of biofilms occurring in...
2.
Thorman A, Reigle J, Chutipongtanate S, Yang J, Shamsaei B, Pilarczyk M, et al.
Sci Adv
. 2024 Aug;
10(35):eadj3010.
PMID: 39213358
We present an in silico approach for drug discovery, dubbed connectivity enhanced structure activity relationship (ceSAR). Building on the landmark LINCS library of transcriptional signatures of drug-like molecules and gene...
3.
DeVore S, Schuetz M, Alvey L, Lujan H, Ochayon D, Williams L, et al.
Cell Rep
. 2024 Aug;
43(8):114589.
PMID: 39110589
Caspase recruitment domain family member 14 (CARD14) and its variants are associated with both atopic dermatitis (AD) and psoriasis, but their mechanistic impact on skin barrier homeostasis is largely unknown....
4.
Webb J, Farrow E, Cain B, Yuan Z, Yarawsky A, Schoch E, et al.
Nucleic Acids Res
. 2024 Jun;
52(13):7987-8002.
PMID: 38874471
The conserved Gsx homeodomain (HD) transcription factors specify neural cell fates in animals from flies to mammals. Like many HD proteins, Gsx factors bind A/T-rich DNA sequences prompting the following...
5.
Xu R, Tiede C, Calabrese A, Cheah L, Adams T, Gauer J, et al.
Blood Adv
. 2024 Jun;
8(15):3917-3928.
PMID: 38838227
Glycoprotein VI (GPVI) plays a key role in collagen-induced platelet aggregation. Affimers are engineered binding protein alternatives to antibodies. We screened and characterized GPVI-binding Affimers as novel tools to probe...
6.
Mills K, Maciag J, Wang C, Crawford J, Enroth T, Keim K, et al.
Cell Rep
. 2024 Apr;
43(4):114022.
PMID: 38568806
Staphylococcus aureus causes the majority of skin and soft tissue infections, but this pathogen only transiently colonizes healthy skin. However, this transient skin exposure enables S. aureus to transition to...
7.
Webb J, Farrow E, Cain B, Yuan Z, Yarawsky A, Schoch E, et al.
bioRxiv
. 2023 Dec;
PMID: 38106145
The conserved Gsx homeodomain (HD) transcription factors specify neural cell fates in animals from flies to mammals. Like many HD proteins, Gsx factors bind A/T-rich DNA sequences prompting the question...
8.
Mills K, Maciag J, Wang C, Crawford J, Enroth T, Keim K, et al.
bioRxiv
. 2023 Dec;
PMID: 38045275
causes the majority of skin and soft tissue infections, but this pathogen only transiently colonizes healthy skin. However, this transient skin exposure enables to transition to infection. Initial adhesion of...
9.
Yarawsky A, Ori A, English L, Whitten S, Herr A
Protein Sci
. 2023 Jun;
32(8):e4707.
PMID: 37334491
Staphylococcus epidermidis and Staphylococcus aureus are highly problematic bacteria in hospital settings. A major challenge is their ability to form biofilms on abiotic or biotic surfaces. Biofilms are well-organized, multicellular...
10.
Smith C, Sonneson G, Hoey R, Hinerman J, Sheehy K, Walter R, et al.
MAbs
. 2023 May;
15(1):2215363.
PMID: 37243579
Camelid heavy-chain-only antibodies are a unique class of antibody that possesses only a single variable domain (termed VHH) for antigen recognition. Despite their apparent canonical mechanism of target recognition, where...