Andres Metspalu
Overview
Explore the profile of Andres Metspalu including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
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433
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54555
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Recent Articles
11.
Suzuki K, Hatzikotoulas K, Southam L, Taylor H, Yin X, Lorenz K, et al.
Nature
. 2024 Feb;
627(8003):347-357.
PMID: 38374256
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes and molecular mechanisms that are often specific to cell type. Here, to characterize the genetic contribution...
12.
Butler-Laporte G, Farjoun J, Nakanishi T, Lu T, Abner E, Chen Y, et al.
Commun Biol
. 2023 Nov;
6(1):1113.
PMID: 37923823
The human leukocyte antigen (HLA) region on chromosome 6 is strongly associated with many immune-mediated and infection-related diseases. Due to its highly polymorphic nature and complex linkage disequilibrium patterns, traditional...
13.
Smid A, Stajdohar M, Milek M, Urbancic D, Kuzelicki N, Tamm R, et al.
Eur J Pharm Sci
. 2023 Oct;
192:106616.
PMID: 37865284
Thiopurine S-methyltransferase (TPMT) is an important enzyme involved in the deactivation of thiopurines and represents a major determinant of thiopurine-related toxicities. Despite its well-known importance in thiopurine metabolism, the understanding...
14.
Budu-Aggrey A, Kilanowski A, Sobczyk M, Shringarpure S, Mitchell R, Reis K, et al.
Nat Commun
. 2023 Oct;
14(1):6172.
PMID: 37794016
Atopic dermatitis (AD) is a common inflammatory skin condition and prior genome-wide association studies (GWAS) have identified 71 associated loci. In the current study we conducted the largest AD GWAS...
15.
Magnussen C, Ojeda F, Leong D, Alegre-Diaz J, Amouyel P, Aviles-Santa L, et al.
N Engl J Med
. 2023 Aug;
389(14):1273-1285.
PMID: 37632466
Background: Five modifiable risk factors are associated with cardiovascular disease and death from any cause. Studies using individual-level data to evaluate the regional and sex-specific prevalence of the risk factors...
16.
Hess T, Maj C, Gehlen J, Borisov O, Haas S, Gockel I, et al.
EBioMedicine
. 2023 Jul;
94:104709.
PMID: 37480624
No abstract available.
17.
Hess T, Maj C, Gehlen J, Borisov O, Haas S, Gockel I, et al.
EBioMedicine
. 2023 May;
92:104616.
PMID: 37209533
Background: Gastric cancer (GC) is clinically heterogenous according to location (cardia/non-cardia) and histopathology (diffuse/intestinal). We aimed to characterize the genetic risk architecture of GC according to its subtypes. Another aim...
18.
Teder-Laving M, Kals M, Reigo A, Ehin R, Objartel T, Vaht M, et al.
Eur J Hum Genet
. 2023 Apr;
32(9):1192.
PMID: 37076744
No abstract available.
19.
Suzuki K, Hatzikotoulas K, Southam L, Taylor H, Yin X, Lorenz K, et al.
medRxiv
. 2023 Apr;
PMID: 37034649
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes. To characterise the genetic contribution to these processes across ancestry groups, we aggregate genome-wide association study...
20.
Teder-Laving M, Kals M, Reigo A, Ehin R, Objartel T, Vaht M, et al.
Eur J Hum Genet
. 2023 Mar;
32(9):1136-1143.
PMID: 36922633
Acne vulgaris is a common chronic skin disorder presenting with comedones, cystic structures forming within the distal hair follicle, and in most cases additionally with inflammatory skin lesions on the...