Andreea-Manuela Mirea
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Explore the profile of Andreea-Manuela Mirea including associated specialties, affiliations and a list of published articles.
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11
Citations
167
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Recent Articles
1.
Cabau G, Gaal O, Badii M, Nica V, Mirea A, Hotea I, et al.
iScience
. 2023 Oct;
26(10):107909.
PMID: 37810213
Gout is an autoinflammatory disease triggered by a complex innate immune response to MSU crystals and inflammatory triggers. While hyperuricemia is an obligatory risk factor for the development of gout,...
2.
Taranu I, Racataianu N, Drugan C, Catana C, Mirea A, Miclea D, et al.
Children (Basel)
. 2023 Jan;
10(1).
PMID: 36670674
Macrophage activation and cytokine release play a pivotal role in inflammation-mediated metabolic disturbances in obesity. The proinflammatory macrophage secretes human chitotriosidase (CHIT1). The expression of the CHIT1 in visceral adipose...
3.
Taranu I, Iancu M, Lazea C, Alkhzouz C, Racataianu N, Catana C, et al.
J Clin Med
. 2022 Jul;
11(13).
PMID: 35806923
Childhood obesity progresses to metabolic disturbances via low-grade inflammation. Identifying novel molecules that reflect the activity of the immune responses is critical in understanding its underlying pathogenesis. Our exploratory study...
4.
Alkhzouz C, Bucerzan S, Miclaus M, Mirea A, Miclea D
Diagnostics (Basel)
. 2021 Aug;
11(8).
PMID: 34441313
Differences in sex development (DSD) in patients with 46,XX karyotype occur by foetal or postnatal exposure to an increased amount of androgens. These disorders are usually diagnosed at birth, in...
5.
Lighezan D, Bojan A, Iancu M, Pop R, Gligor-Popa S, Tripon F, et al.
J Pers Med
. 2020 Dec;
10(4).
PMID: 33271790
Background: The complexity of myeloproliferative neoplasms (MPNs) cannot be characterized by acquired somatic mutations alone. Individual genetic background is thought to contribute to the development of MPNs. The aim of...
6.
Mirea A, Pop R, Cainap S, Trifa A
Eur J Med Genet
. 2020 Nov;
63(12):104100.
PMID: 33186763
Vitamin D plays an important role in calcium homeostasis and bone mineralization. Inefficient inactivation of vitamin D leads to a condition called idiopathic infantile hypercalcemia (IIH). In the last decade...
7.
Mirea A, Stienstra R, Kanneganti T, Tack C, Chavakis T, Toonen E, et al.
Inflammation
. 2020 Feb;
43(3):1054-1064.
PMID: 32002713
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease. Inflammatory pathways contribute to disease pathogenesis; however, regulation of the underlying mechanism is not completely understood....
8.
Mirea A, Toonen E, van den Munckhof I, Munsterman I, Tjwa E, Jaeger M, et al.
Mol Med
. 2019 May;
25(1):16.
PMID: 31046673
Introduction: Non-alcoholic fatty liver disease (NAFLD) is becoming a major health problem worldwide. Inflammation plays an important role in disease pathogenesis and recent studies have shown a potential role for...
9.
Boutens L, Mirea A, van den Munckhof I, Doppenberg-Oosting M, Jaeger M, Hijmans A, et al.
Cytokine
. 2018 Apr;
108:205-212.
PMID: 29698883
Toll like receptors (TLRs) are expressed in adipose tissue and promote adipose tissue inflammation during obesity. Recently, anti-inflammatory properties have been attributed to TLR10 in myeloid cells, the only member...
10.
Mirea A, Tack C, Chavakis T, Joosten L, Toonen E
Trends Mol Med
. 2018 Apr;
24(5):458-471.
PMID: 29665983
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. Pathways responsible for the activation of IL-1 family cytokines are key in the development of NAFLD but underlying...