Andreas Schlicker
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Explore the profile of Andreas Schlicker including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Quanz M, Bender E, Kopitz C, Grunewald S, Schlicker A, Schwede W, et al.
Mol Cancer Ther
. 2018 Aug;
17(11):2285-2296.
PMID: 30115664
The lactate transporter /monocarboxylate transporter 1 (MCT1) plays a central role in tumor cell energy homeostasis. In a cell-based screen, we identified a novel class of MCT1 inhibitors, including BAY-8002,...
12.
Klutzny S, Lesche R, Keck M, Kaulfuss S, Schlicker A, Christian S, et al.
Cell Death Dis
. 2017 Mar;
8(3):e2709.
PMID: 28358364
Owing to lagging or insufficient neo-angiogenesis, hypoxia is a feature of most solid tumors. Hypoxic tumor regions contribute to resistance against antiproliferative chemotherapeutics, radiotherapy and immunotherapy. Targeting cells in hypoxic...
13.
Schlicker A, Michaut M, Rahman R, Wessels L
Sci Rep
. 2016 Jun;
6:28103.
PMID: 27321817
Although large-scale efforts for molecular profiling of cancer samples provide multiple data types for many samples, most approaches for finding candidate cancer genes rely on somatic mutations and DNA copy...
14.
Vecchione L, Gambino V, Raaijmakers J, Schlicker A, Fumagalli A, Russo M, et al.
Cell
. 2016 Apr;
165(2):317-30.
PMID: 27058664
BRAF(V600E) mutant colon cancers (CCs) have a characteristic gene expression signature that is also found in some tumors lacking this mutation. Collectively, they are referred to as "BRAF-like" tumors and...
15.
Heynen G, Nevedomskaya E, Palit S, Jagalur Basheer N, Lieftink C, Schlicker A, et al.
Mol Cancer Res
. 2016 Jan;
14(5):411-22.
PMID: 26785999
Unlabelled: Neuroblastoma cell lines can differentiate upon treatment with retinoic acid (RA), a finding that provided the basis for the clinical use of RA to treat neuroblastoma. However, resistance to...
16.
Michaut M, Chin S, Majewski I, Severson T, Bismeijer T, De Koning L, et al.
Sci Rep
. 2016 Jan;
6:18517.
PMID: 26729235
Invasive lobular carcinoma (ILC) is the second most frequently occurring histological breast cancer subtype after invasive ductal carcinoma (IDC), accounting for around 10% of all breast cancers. The molecular processes...
17.
Iskit S, Schlicker A, Wessels L, Peeper D
Oncotarget
. 2015 Dec;
6(41):43146-61.
PMID: 26646695
Fra-1 (Fos-related antigen-1) is a member of the AP-1 (activator protein-1) family of transcription factors. We previously showed that Fra-1 is necessary for breast cancer cells to metastasize in vivo,...
18.
Guinney J, Dienstmann R, Wang X, De Reynies A, Schlicker A, Soneson C, et al.
Nat Med
. 2015 Oct;
21(11):1350-6.
PMID: 26457759
Colorectal cancer (CRC) is a frequently lethal disease with heterogeneous outcomes and drug responses. To resolve inconsistencies among the reported gene expression-based CRC classifications and facilitate clinical translation, we formed...
19.
Henneman L, van Miltenburg M, Michalak E, Braumuller T, Jaspers J, Drenth A, et al.
Proc Natl Acad Sci U S A
. 2015 Jun;
112(27):8409-14.
PMID: 26100884
Metaplastic breast carcinoma (MBC) is a rare histological breast cancer subtype characterized by mesenchymal elements and poor clinical outcome. A large fraction of MBCs harbor defects in breast cancer 1...
20.
Groenendijk F, De Jong J, Fransen van de Putte E, Michaut M, Schlicker A, Peters D, et al.
Eur Urol
. 2015 Feb;
69(3):384-8.
PMID: 25636205
Unlabelled: A pathologic complete response to neoadjuvant chemotherapy (NAC) containing platinum is a strong prognostic determinant for patients with muscle-invasive bladder cancer (MIBC). Despite comprehensive molecular characterization of bladder cancer,...