Andreas Gerasch
Overview
Explore the profile of Andreas Gerasch including associated specialties, affiliations and a list of published articles.
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10
Citations
278
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Recent Articles
1.
Stockel D, Kehl T, Trampert P, Schneider L, Backes C, Ludwig N, et al.
Bioinformatics
. 2016 Jan;
32(10):1502-8.
PMID: 26787660
Motivation: Gene set analysis has revolutionized the interpretation of high-throughput transcriptomic data. Nowadays, with comprehensive studies that measure multiple -omics from the same sample, powerful tools for the integrative analysis...
2.
Schneider L, Stockel D, Kehl T, Gerasch A, Ludwig N, Leidinger P, et al.
Int J Cancer
. 2015 Oct;
138(7):1765-76.
PMID: 26501925
Cancer is a large class of diseases that are characterized by a common set of features, known as the Hallmarks of cancer. One of these hallmarks is the acquisition of...
3.
Gerasch A, Faber D, Kuntzer J, Niermann P, Kohlbacher O, Lenhof H, et al.
PLoS One
. 2014 Feb;
9(2):e87397.
PMID: 24551056
Interactive visual analysis of biological high-throughput data in the context of the underlying networks is an essential task in modern biomedicine with applications ranging from metabolic engineering to personalized medicine....
4.
Stockel D, Muller O, Kehl T, Gerasch A, Backes C, Rurainski A, et al.
Bioinformatics
. 2013 Apr;
29(13):1702-3.
PMID: 23625999
Unlabelled: The deregulation of biochemical pathways plays a central role in many diseases like cancer or Parkinsons's disease. In silico tools for calculating these deregulated pathways may help to gain...
5.
Laczny C, Leidinger P, Haas J, Ludwig N, Backes C, Gerasch A, et al.
BMC Bioinformatics
. 2012 Feb;
13:36.
PMID: 22356618
Background: Expression profiling provides new insights into regulatory and metabolic processes and in particular into pathogenic mechanisms associated with diseases. Besides genes, non-coding transcripts as microRNAs (miRNAs) gained increasing relevance...
6.
Backes C, Rurainski A, Klau G, Muller O, Stockel D, Gerasch A, et al.
Nucleic Acids Res
. 2012 Jan;
40(6):e43.
PMID: 22210863
Deregulation of cell signaling pathways plays a crucial role in the development of tumors. The identification of such pathways requires effective analysis tools that facilitate the interpretation of expression differences....
7.
Hoppe A, Hoffmann S, Gerasch A, Gille C, Holzhutter H
BMC Bioinformatics
. 2011 Jan;
12:28.
PMID: 21255455
Background: Flux-balance analysis based on linear optimization is widely used to compute metabolic fluxes in large metabolic networks and gains increasingly importance in network curation and structural analysis. Thus, a...
8.
A novel algorithm for detecting differentially regulated paths based on gene set enrichment analysis
Keller A, Backes C, Gerasch A, Kaufmann M, Kohlbacher O, Meese E, et al.
Bioinformatics
. 2009 Aug;
25(21):2787-94.
PMID: 19713416
Motivation: Deregulated signaling cascades are known to play a crucial role in many pathogenic processes, among them are tumor initiation and progression. In the recent past, modern experimental techniques that...
9.
Keller A, Backes C, Al-Awadhi M, Gerasch A, Kuntzer J, Kohlbacher O, et al.
BMC Bioinformatics
. 2008 Dec;
9:552.
PMID: 19099609
Background: High-throughput methods that allow for measuring the expression of thousands of genes or proteins simultaneously have opened new avenues for studying biochemical processes. While the noisiness of the data...
10.
Kuntzer J, Backes C, Blum T, Gerasch A, Kaufmann M, Kohlbacher O, et al.
BMC Bioinformatics
. 2007 Oct;
8:367.
PMID: 17910766
Background: Technological advances in high-throughput techniques and efficient data acquisition methods have resulted in a massive amount of life science data. The data is stored in numerous databases that have...