Andreas Keller
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Explore the profile of Andreas Keller including associated specialties, affiliations and a list of published articles.
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383
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13305
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Recent Articles
1.
Grandke F, Fehlmann T, Kern F, Gate D, Wolff T, Leventhal O, et al.
Nat Commun
. 2025 Feb;
16(1):1965.
PMID: 40000636
The clinical course and treatment of neurodegenerative disease are complicated by immune-system interference and chronic inflammatory processes, which remain incompletely understood. Mapping immune signatures in larger human cohorts through single-cell...
2.
Hart M, Diener C, Rheinheimer S, Kehl T, Keller A, Lenhof H, et al.
RNA Biol
. 2025 Jan;
22(1):1-9.
PMID: 39760255
The lack of a sufficient number of validated miRNA targets severely hampers the understanding of their biological function. Even for the well-studied miR-155-5p, there are only 239 experimentally validated targets...
3.
Di Santo S, Dipoppa M, Keller A, Roth M, Scanziani M, Miller K
Cell Rep
. 2024 Dec;
44(1):115088.
PMID: 39709599
Sensory systems use context to infer meaning. Accordingly, context profoundly influences neural responses to sensory stimuli. However, a cohesive understanding of the circuit mechanisms governing contextual effects across different stimulus...
4.
Molano L, Hirsch P, Hannig M, Muller R, Keller A
Nucleic Acids Res
. 2024 Nov;
53(D1):D189-D196.
PMID: 39565221
Plasmids are extrachromosomal DNA molecules in bacteria and archaea, playing critical roles in horizontal gene transfer, antibiotic resistance, and pathogenicity. Since its first release in 2018, our database on plasmids,...
5.
Oesinghaus L, Castillo-Hair S, Ludwig N, Keller A, Seelig G
bioRxiv
. 2024 Nov;
PMID: 39554011
Limiting expression to target cell types is a longstanding goal in gene therapy, which could be met by sensing endogenous microRNA. However, an unclear association between microRNA expression and activity...
6.
Rishik S, Hirsch P, Grandke F, Fehlmann T, Keller A
Nucleic Acids Res
. 2024 Nov;
53(D1):D129-D137.
PMID: 39540421
MiRNAs represent a non-coding RNA class that regulate gene expression and pathways. While miRNAs are evolutionary conserved most data stems from Homo sapiens and Mus musculus. As miRNA expression is...
7.
Diener C, Thure K, Engel A, Hart M, Keller A, Meese E, et al.
Eur J Cell Biol
. 2024 Sep;
103(4):151458.
PMID: 39341198
Mesenchymal Stem Cells (MSCs) derived from the embryonic mesoderm persist as a viable source of multipotent cells in adults and have a crucial role in tissue repair. One of the...
8.
Schmartz G, Rehner J, Gund M, Keller V, Molano L, Rupf S, et al.
Nat Commun
. 2024 Sep;
15(1):8261.
PMID: 39327438
The human microbiome emerges as a promising reservoir for diagnostic markers and therapeutics. Since host-associated microbiomes at various body sites differ and diseases do not occur in isolation, a comprehensive...
9.
Schmartz G, Rehner J, Schuff M, Molano L, Becker S, Krawczyk M, et al.
Nat Commun
. 2024 Sep;
15(1):8263.
PMID: 39327429
Understanding human, animal, and environmental microbiota is essential for advancing global health and combating antimicrobial resistance (AMR). We investigate the oral and gut microbiota of 48 animal species in captivity,...
10.
Yu Z, Sasidharan-Nair V, Buchta T, Bonifacius A, Khan F, Pietzsch B, et al.
PLoS Pathog
. 2024 Sep;
20(9):e1012581.
PMID: 39325839
Epigenetic mechanisms stabilize gene expression patterns during CD8+ T cell differentiation. Although adoptive transfer of virus-specific T cells is clinically applied to reduce the risk of virus infection or reactivation...