Andreas Friebe
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Explore the profile of Andreas Friebe including associated specialties, affiliations and a list of published articles.
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75
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1677
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Recent Articles
1.
Kreutz L, Gaab A, Dona M, Pinto A, Tallquist M, Groneberg D, et al.
iScience
. 2025 Jan;
28(1):111615.
PMID: 39829679
NO-sensitive guanylyl cyclase (NO-GC) is involved in the (patho)physiology of the mammalian heart. However, little is known about the individual cardiac cell types that express NO-GC and the role of...
2.
Korkmaz Y, Pryymachuk G, Schroeter M, Puladi B, Piekarek N, Appel S, et al.
Int J Mol Sci
. 2025 Jan;
26(1.
PMID: 39795887
Nitric oxide-sensitive guanylyl cyclase (NO-GC) is a heterodimeric enzyme with an α- and a β-subunit. In its active form as an αβ-heterodimer, NO-GC produces cyclic guanosine-3',5'-monophophate (cGMP) to regulate vasodilation...
3.
Khan M, Fischer J, Harrer L, Schwiering F, Groneberg D, Friebe A
Sci Rep
. 2024 Aug;
14(1):18840.
PMID: 39138336
The combination of lineage tracing and immunohistochemistry has helped to identify subpopulations and fate of hepatic stellate cells (HSC) in murine liver. HSC are sinusoidal pericytes that act as myofibroblast...
4.
Balmes A, Rodriguez J, Seifert J, Pinto-Quintero D, Khawaja A, Boffito M, et al.
Platelets
. 2024 Feb;
35(1):2313359.
PMID: 38353233
Cyclic guanosine monophosphate (cGMP) is a second messenger produced by the NO-sensitive guanylyl cyclase (NO-GC). The NO-GC/cGMP pathway in platelets has been extensively studied. However, its role in regulating the...
5.
Alexander S, Fabbro D, Kelly E, Mathie A, Peters J, Veale E, et al.
Br J Pharmacol
. 2023 Dec;
180 Suppl 2:S241-S288.
PMID: 38123155
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of...
6.
Englert N, Burkard P, Aue A, Rosenwald A, Nieswandt B, Friebe A
Int J Mol Sci
. 2023 Jul;
24(14).
PMID: 37511420
Pulmonary fibrosis is a chronic and progressive disease with limited therapeutic options. Nitric oxide (NO) is suggested to reduce the progression of pulmonary fibrosis via NO-sensitive guanylyl cyclase (NO-GC). The...
7.
Mauersberger C, Sager H, Wobst J, Dang T, Lambrecht L, Koplev S, et al.
Nat Cardiovasc Res
. 2023 Jul;
1(12):1174-1186.
PMID: 37484062
Variants in genes encoding the soluble guanylyl cyclase (sGC) in platelets are associated with coronary artery disease (CAD) risk. Here, by using histology, flow cytometry and intravital microscopy, we show...
8.
Aue A, Englert N, Harrer L, Schwiering F, Gaab A, Konig P, et al.
Respir Res
. 2023 Jun;
24(1):167.
PMID: 37349733
Background: The origin of αSMA-positive myofibroblasts, key players within organ fibrosis, is still not fully elucidated. Pericytes have been discussed as myofibroblast progenitors in several organs including the lung. Methods:...
9.
Friebe A, Kraehling J, Russwurm M, Sandner P, Schmidtko A
Naunyn Schmiedebergs Arch Pharmacol
. 2023 Apr;
396(8):1669-1686.
PMID: 37079081
Increasing cGMP is a unique therapeutic principle, and drugs inhibiting cGMP-degrading enzymes or stimulating cGMP production are approved for the treatment of various diseases such as erectile dysfunction, coronary artery...
10.
Breitenbach T, Englert N, Osmanoglu O, Rukoyatkina N, Wangorsch G, Heinze K, et al.
J Theor Biol
. 2022 Jul;
550:111222.
PMID: 35843440
Background: The cyclic nucleotides cAMP and cGMP inhibit platelet activation. Different platelet signaling modules work together. We develop here a modelling framework to integrate different signaling modules and apply it...