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Andreas Alvin Purnomo Soetedjo

Explore the profile of Andreas Alvin Purnomo Soetedjo including associated specialties, affiliations and a list of published articles. Areas
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Citations 55
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Recent Articles
1.
Soetedjo A, Lee J, Lau H, Goh G, An J, Koh Y, et al.
Trends Endocrinol Metab . 2021 Jun; 32(8):609-622. PMID: 34154916
Diabetes is a severe chronic disease worldwide. In various types of diabetes, the pancreatic beta cells fail to secrete sufficient insulin, at some point, to regulate blood glucose levels. Therefore,...
2.
Loo L, Soetedjo A, Lau H, Ng N, Ghosh S, Nguyen L, et al.
Cell Death Dis . 2020 May; 11(5):378. PMID: 32424151
The differentiation of human pluripotent stem cells into pancreatic cells involves cellular proliferation and apoptosis during cell fate transitions. However, their implications for establishing cellular identity are unclear. Here, we...
3.
Neo C, Ciaramicoli L, Soetedjo A, Teo A, Kang N
Semin Cell Dev Biol . 2020 Feb; 103:3-13. PMID: 32057664
Beta cells assume a fundamental role in maintaining blood glucose homeostasis through the secretion of insulin, which is contingent on both beta cell mass and function, in response to elevated...
4.
Loo L, Vethe H, Soetedjo A, Paulo J, Jasmen J, Jackson N, et al.
Stem Cells . 2019 Dec; 38(4):542-555. PMID: 31828876
A comprehensive characterization of the molecular processes controlling cell fate decisions is essential to derive stable progenitors and terminally differentiated cells that are functional from human pluripotent stem cells (hPSCs)....
5.
Kang N, Soetedjo A, Amirruddin N, Chang Y, Eriksson O, Teo A
Trends Mol Med . 2019 Jun; 25(8):708-722. PMID: 31178230
When diabetes is diagnosed, the majority of insulin-secreting pancreatic β cells are already dysfunctional or destroyed. This β cell dysfunction/destruction usually takes place over many years, making timely detection and...