Andrea S Heimann
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Explore the profile of Andrea S Heimann including associated specialties, affiliations and a list of published articles.
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19
Citations
437
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Recent Articles
1.
Murphy M, Rollins A, Heimann A, Fang J, Krongrad A
Vet J
. 2024 May;
305:106144.
PMID: 38788998
Oral consumption of Pep19™, a 10 amino acid intracellular peptide, has been associated with weight loss in rodents and humans via induction of nonshivering thermogenesis. This study aimed to test...
2.
Silverio R, Barth R, Heimann A, Reckziegel P, Dos Santos G, Romero-Zerbo S, et al.
Int J Mol Sci
. 2022 Apr;
23(8).
PMID: 35456900
Peptide DIIADDEPLT (Pep19) has been previously suggested to improve metabolic parameters, without adverse central nervous system effects, in a murine model of diet-induced obesity. Here, we aimed to further evaluate...
3.
Sakaya G, Parada C, Eichler R, Yamaki V, Navon A, Heimann A, et al.
J Proteomics
. 2021 Mar;
240:104188.
PMID: 33781962
Intracranial saccular aneurysms (ISA) represent 90%-95% of all intracranial aneurysm cases, characterizing abnormal pockets at arterial branch points. Ruptures lead to subarachnoid hemorrhages (SAH) and poor prognoses. We applied mass...
4.
Heimann A, Dale C, Guimaraes F, Reis R, Navon A, Shmuelov M, et al.
Neuropharmacology
. 2020 Nov;
183:108406.
PMID: 33212113
Hemopressin (PVNFKFLSH in rats, and PVNFKLLSH in humans and mice), a fragment derived from the α-chain of hemoglobin, was the first peptide described to have type 1 cannabinoid receptor activity....
5.
Heimann A, Giardini A, SantAnna M, Dos Santos N, Gewehr M, Munhoz C, et al.
Neurosci Lett
. 2020 Feb;
721:134765.
PMID: 32004656
Previous studies suggested the pharmacological potential of rat hemopressin (PVNFKFLSH) and its shorter synthetic peptide NFKF, to protect from pilocarpine-induced seizures in mice. Orally administered NFKF was shown to be...
6.
de Araujo C, Heimann A, Remer R, Russo L, Colquhoun A, Forti F, et al.
Biomolecules
. 2019 Apr;
9(4).
PMID: 30995799
Intracellular peptides are produced by proteasomes following degradation of nuclear, cytosolic, and mitochondrial proteins, and can be further processed by additional peptidases generating a larger pool of peptides within cells....
7.
Heimann A, Gupta A, Gomes I, Rahman R, Schlessinger A, Ferro E, et al.
PLoS One
. 2018 Feb;
13(2):e0193322.
PMID: 29447277
[This corrects the article DOI: 10.1371/journal.pone.0187306.].
8.
Reckziegel P, Festuccia W, Britto L, Jang K, Romao C, Heimann J, et al.
Sci Rep
. 2017 Nov;
7(1):14781.
PMID: 29093454
Intracellular peptides generated by limited proteolysis are likely to function inside and outside cells and could represent new possibilities for drug development. Here, we used several conformational-sensitive antibodies targeting G-protein...
9.
Heimann A, Gupta A, Gomes I, Rayees R, Schlessinger A, Ferro E, et al.
PLoS One
. 2017 Nov;
12(11):e0187306.
PMID: 29091950
The N-terminal region of G protein-coupled receptors can be efficiently targeted for the generation of receptor-selective antibodies. These antibodies are useful for the biochemical characterization of the receptors. In this...
10.
Toniolo E, Maique E, Ferreira Jr W, Heimann A, Ferro E, Ramos-Ortolaza D, et al.
Peptides
. 2014 Apr;
56:125-31.
PMID: 24703998
Direct-acting cannabinoid receptor ligands are well known to reduce hyperalgesic responses after nerve injury, although their psychoactive side effects have damped enthusiasm for their therapeutic development. Hemopressin (Hp) is a...