Ellen M Unterwald
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Explore the profile of Ellen M Unterwald including associated specialties, affiliations and a list of published articles.
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80
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Recent Articles
1.
Mokkarala P, Wiah S, Unterwald E, Shi X, Stern D, Stern D, et al.
Neurosci Res
. 2025 Feb;
PMID: 39894415
NA-014 is a positive allosteric modulator (PAM) of glutamate transporter subtype 1 (GLT-1) that increases glutamate reuptake. Since enhanced glutamate transmission facilitates methamphetamine (METH) hyperlocomotion, behavioral sensitization, and conditioned place...
2.
Bhoj P, Nocito C, Togre N, Winfield M, Lubinsky C, Khan S, et al.
Int J Mol Sci
. 2024 Sep;
25(18).
PMID: 39337564
Excessive production and response to Type I interferons (IFNs) is a hallmark of systemic lupus erythematosus (SLE). Neuropsychiatric lupus (NPSLE) is a common manifestation of human SLE, with major depression...
3.
Brailoiu E, Barr J, Wittorf H, Inan S, Unterwald E, Brailoiu G
Int J Mol Sci
. 2024 May;
25(10).
PMID: 38791182
Sigma non-opioid intracellular receptor 1 (Sigma-1R) is an intracellular chaperone protein residing on the endoplasmic reticulum at the mitochondrial-associated membrane (MAM) region. Sigma-1R is abundant in the brain and is...
4.
Li C, McElroy B, Phillips J, McCloskey N, Shi X, Unterwald E, et al.
J Psychopharmacol
. 2024 Jan;
38(2):188-199.
PMID: 38293836
Background: The serotonin (5-hydroxytryptamine (5-HT))-mediated system plays an important role in stress-related psychiatric disorders and substance abuse. Our previous studies showed that stress and drug exposure can modulate the dorsal...
5.
Caban Rivera C, Price R, Fortuna R, Li C, Do C, Shinkle J, et al.
bioRxiv
. 2023 Dec;
PMID: 38076811
Drug craving triggered by cues that were once associated with drug intoxication is a major contributor to continued drug-seeking behaviors. Addictive drugs engage molecular pathways of associative learning and memory....
6.
Unterwald E, Rawls S
J Pharmacol Exp Ther
. 2023 May;
385(3):159-161.
PMID: 37197988
No abstract available.
7.
Shi X, von Weltin E, Fitzsimmons E, Do C, Caban Rivera C, Chen C, et al.
Front Pharmacol
. 2022 Oct;
13:976932.
PMID: 36238569
Mechanistic target of rapamycin (mTOR) C1 and its downstream effectors have been implicated in synaptic plasticity and memory. Our prior work demonstrated that reactivation of cocaine memory engages a signaling...
8.
Denny R, Connelly K, Ghilotti M, Meissler J, Yu D, Eisenstein T, et al.
Front Neurosci
. 2022 Jan;
15:772946.
PMID: 34975380
Post-traumatic stress disorder (PTSD) is initiated by traumatic-stress exposure and manifests into a collection of symptoms including increased anxiety, sleep disturbances, enhanced response to triggers, and increased sympathetic nervous system...
9.
Leger R, Unterwald E
J Psychopharmacol
. 2021 Sep;
36(1):20-30.
PMID: 34519567
Background: Classical psychedelics are a group of drugs which act as agonists on the serotonin-2A (5-HT2A) receptor. Evidence suggests they may have a uniquely rapid and enduring positive effect on...
10.
Crittenden J, Zhai S, Sauvage M, Kitsukawa T, Burguiere E, Thomsen M, et al.
Neurobiol Dis
. 2021 Aug;
158:105473.
PMID: 34371144
CalDAG-GEFI (CDGI) is a protein highly enriched in the striatum, particularly in the principal spiny projection neurons (SPNs). CDGI is strongly down-regulated in two hyperkinetic conditions related to striatal dysfunction:...