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Andrea Pierleoni

Explore the profile of Andrea Pierleoni including associated specialties, affiliations and a list of published articles. Areas
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Citations 1284
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Recent Articles
1.
Ochoa D, Hercules A, Carmona M, Suveges D, Gonzalez-Uriarte A, Malangone C, et al.
Nucleic Acids Res . 2020 Nov; 49(D1):D1302-D1310. PMID: 33196847
The Open Targets Platform (https://www.targetvalidation.org/) provides users with a queryable knowledgebase and user interface to aid systematic target identification and prioritisation for drug discovery based upon underlying evidence. It is...
2.
Carvalho-Silva D, Pierleoni A, Pignatelli M, Ong C, Fumis L, Karamanis N, et al.
Nucleic Acids Res . 2018 Nov; 47(D1):D1056-D1065. PMID: 30462303
The Open Targets Platform integrates evidence from genetics, genomics, transcriptomics, drugs, animal models and scientific literature to score and rank target-disease associations for drug target identification. The associations are displayed...
3.
Cano-Rodriguez D, Campagnoli S, Grandi A, Parri M, De Camilli E, Song C, et al.
Oncotarget . 2017 Dec; 8(56):95256-95269. PMID: 29221125
Tectonic family member 2 () encodes a transmembrane protein that belongs to the tectonic family, which is involved in ciliary functions. Previous studies have demonstrated the role of tectonics in...
4.
Koscielny G, An P, Carvalho-Silva D, Cham J, Fumis L, Gasparyan R, et al.
Nucleic Acids Res . 2016 Dec; 45(D1):D985-D994. PMID: 27899665
We have designed and developed a data integration and visualization platform that provides evidence about the association of known and potential drug targets with diseases. The platform is designed to...
5.
Bartolini E, Ianni E, Frigimelica E, Petracca R, Galli G, Scorza F, et al.
J Extracell Vesicles . 2013 Sep; 2. PMID: 24009891
Background: Outer membrane vesicles (OMVs) are spheroid particles released by all Gram-negative bacteria as a result of the budding out of the outer membrane. Since they carry many of the...
6.
Grifantini R, Pagani M, Pierleoni A, Grandi A, Parri M, Campagnoli S, et al.
J Proteomics . 2011 Sep; 75(2):532-47. PMID: 21920474
The YOMICS™ antibody library (http://www.yomics.com/) presented in this article is a new collection of 1559 murine polyclonal antibodies specific for 1287 distinct human proteins. This antibody library is designed to...
7.
Savojardo C, Fariselli P, Alhamdoosh M, Martelli P, Pierleoni A, Casadio R
Bioinformatics . 2011 Jul; 27(16):2224-30. PMID: 21715467
Motivation: Disulfide bonds stabilize protein structures and play relevant roles in their functions. Their formation requires an oxidizing environment and their stability is consequently depending on the redox ambient potential,...
8.
Pierleoni A, Indio V, Savojardo C, Fariselli P, Martelli P, Casadio R
Nucleic Acids Res . 2011 May; 39(Web Server issue):W375-80. PMID: 21543452
MemPype is a Python-based pipeline including previously published methods for the prediction of signal peptides (SPEP), glycophosphatidylinositol (GPI) anchors (PredGPI), all-alpha membrane topology (ENSEMBLE), and a recent method (MemLoci) that...
9.
Pierleoni A, Martelli P, Casadio R
Bioinformatics . 2011 Mar; 27(9):1224-30. PMID: 21367869
Motivation: Subcellular localization is a key feature in the process of functional annotation of both globular and membrane proteins. In the absence of experimental data, protein localization is inferred on...
10.
Juncker A, Jensen L, Pierleoni A, Bernsel A, Tress M, Bork P, et al.
Genome Biol . 2009 Feb; 10(2):206. PMID: 19226438
A recent trend in computational methods for annotation of protein function is that many prediction tools are combined in complex workflows and pipelines to facilitate the analysis of feature combinations,...