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Andrea Pennati

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Articles 28
Citations 365
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Recent Articles
1.
Fenske R, Wienkes H, Peter D, Schaid M, Hurley L, Pennati A, et al.
J Endocr Soc . 2024 Jun; 8(7):bvae100. PMID: 38831864
Prostaglandin E (PGE) is a key mediator of inflammation and is derived from the omega-6 polyunsaturated fatty acid, arachidonic acid (AA). In the β-cell, the PGE receptor, Prostaglandin EP3 receptor...
2.
Blitzer G, Paz C, Glassey A, Ganz O, Giri J, Pennati A, et al.
Radiother Oncol . 2024 Jan; 192:110093. PMID: 38224919
Purpose: Salivary dysfunction is a significant side effect of radiation therapy for head and neck cancer (HNC). Preliminary data suggests that mesenchymal stromal cells (MSCs) can improve salivary function. Whether...
3.
McCoy S, Parker M, Gurevic I, Das R, Pennati A, Galipeau J
Rheumatology (Oxford) . 2022 Feb; 61(10):4207-4218. PMID: 35218354
Objectives: Sjögren's disease (SjD) is a systemic autoimmune disease characterized by focal lymphocytic infiltrate of salivary glands (SGs) and high SG IFNγ, both of which are associated with elevated lymphoma...
4.
Ramesha S, Rayaprolu S, Bowen C, Giver C, Bitarafan S, Nguyen H, et al.
Proc Natl Acad Sci U S A . 2021 Mar; 118(11). PMID: 33649184
Kv1.3 potassium channels, expressed by proinflammatory central nervous system mononuclear phagocytes (CNS-MPs), are promising therapeutic targets for modulating neuroinflammation in Alzheimer's disease (AD). The molecular characteristics of Kv1.3-high CNS-MPs and...
5.
McCoy S, Giri J, Das R, Paul P, Pennati A, Parker M, et al.
Cytotherapy . 2020 Dec; 23(4):301-310. PMID: 33262072
Background Aims: Mesenchymal stromal cells (MSCs) provide minor salivary glands (MSGs) with support and niche cells for epithelial glandular tissue. Little is known about resident MSG-derived MSCs (MSG-MSCs) in primary...
6.
Pennati A, Apfelbeck T, Brounts S, Galipeau J
Tissue Eng Part A . 2020 Aug; 27(9-10):582-592. PMID: 32854583
Mammalian platelets participate in the immediate tissue injury response by initiating coagulation and further promoting tissue injury mitigation and repair. The latter properties are deployed following platelet release of presynthetized...
7.
Pennati A, Nylen E, Duncan I, Galipeau J
J Neurosci . 2020 May; 40(26):5105-5115. PMID: 32430295
The unmet medical need of patients with multiple sclerosis (MS) is the inexorable loss of CNS myelin and latterly neurons leading to permanent neurologic disability. Solicitation of endogenous oligodendrocytes progenitor...
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Rangaraju S, Raza S, Pennati A, Deng Q, Dammer E, Duong D, et al.
J Neuroinflammation . 2017 Jun; 14(1):128. PMID: 28651603
Background: Kv1.3 potassium channels regulate microglial functions and are overexpressed in neuroinflammatory diseases. Kv1.3 blockade may selectively inhibit pro-inflammatory microglia in neurological diseases but the molecular and cellular mechanisms regulated...
10.
Deng J, Li Y, Pennati A, Yuan S, Wu J, Waller E, et al.
Mol Ther . 2017 Feb; 25(2):416-426. PMID: 28153092
Hematopoietic stem cells (HSCs) have the capacity to self-renew and differentiate into hematopoietic cells and have been utilized to replace diseased bone marrow for patients with cancers and blood disorders....