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Andrea L George

Explore the profile of Andrea L George including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 348
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Recent Articles
1.
Sakakibara N, Clavijo P, Sievers C, Gray V, King K, George A, et al.
Front Immunol . 2023 Aug; 14:1200970. PMID: 37638000
Introduction: Amplification of human chromosome 3q26-29, which encodes oncoprotein ΔNp63 among other isoforms of the p63 family, is a feature common to squamous cell carcinomas (SCCs) of multiple tissue origins....
2.
Moses M, George A, Sakakibara N, Mahmood K, Ponnamperuma R, King K, et al.
Int J Mol Sci . 2019 Jul; 20(14). PMID: 31340447
The gene is a member of the p53/p63/p73 family of transcription factors and plays a critical role in development and homeostasis of squamous epithelium. is transcribed as multiple isoforms; ΔNp63α,...
3.
King K, George A, Sakakibara N, Mahmood K, Moses M, Weinberg W
Mol Carcinog . 2019 Jul; 58(9):1571-1580. PMID: 31286584
Overexpression of ΔNp63α, a member of the p53/p63/p73 family of transcription factors, is a molecular attribute of human squamous cancers of the head and neck, lung and skin. The TP63...
4.
George A, Boulanger C, Anderson L, Cagnet S, Brisken C, Smith G
J Cell Sci . 2017 Apr; 130(12):2018-2025. PMID: 28455412
Amphiregulin (AREG) mice demonstrate impaired mammary development and form only rudimentary ductal epithelial trees; however, AREG glands are still capable of undergoing alveologenesis and lactogenesis during pregnancy. Transplantation of AREG...
5.
Bruno R, Fleming J, George A, Boulanger C, Schedin P, Smith G
Sci Rep . 2017 Jan; 7:40196. PMID: 28071703
Previously, we demonstrated the ability of the normal mammary microenvironment (niche) to direct non-mammary cells including testicular and embryonic stem cells (ESCs) to adopt a mammary epithelial cell (MEC) fate....
6.
George A, Smith G
Int J Stem Cell Res Ther . 2016 Jul; 3(1). PMID: 27453956
Implants of mammary glands from a single mammary fat pad in a H253 transgenic female mouse heterozygous for a lacZ-labeled X chromosome were analyzed at various time points following transplantation...
7.
George A, Boulanger C, Smith G
Aging (Albany NY) . 2016 Jun; 8(7):1353-63. PMID: 27347776
It has been proposed that the erosion of telomere length is a limiting factor in replicative capacity and important in cell senescence. To determine if this activity was essential in...
8.
George A, Suriano R, Rajoria S, Osso M, Tuli N, Hanly E, et al.
J Cancer . 2015 Dec; 6(12):1320-30. PMID: 26640592
Over expression of various immunogenic melanoma associated antigens (MAAs) has been exploited in the development of immunotherapeutic melanoma vaccines. Expression of MAAs such as MART-1 and gp100 is modulated by...
9.
Boulanger C, Rosenfield S, George A, Smith G
J Mammary Gland Biol Neoplasia . 2015 Sep; 20(1-2):93-101. PMID: 26362796
Mammotropic hormones and growth factors play a very important role in mammary growth and differentiation. Here, hormones including Estrogen, Progesterone, Prolactin, their cognate receptors, and the growth factor Amphiregulin, are...
10.
Hanly E, Rajoria S, Darzynkiewicz Z, Zhao H, Suriano R, Tuli N, et al.
BMC Res Notes . 2014 Mar; 7:187. PMID: 24673746
Background: Thyroid cancer is the most common endocrine-related cancer in the United States and its incidence is rising rapidly. Since among various genetic lesions identified in thyroid cancer, the BRAFV600E...