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Andrea Jacobs

Explore the profile of Andrea Jacobs including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 2212
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Recent Articles
21.
Hartmann J, Tran T, Kaudeer J, Oberle K, Herrmann J, Quagliano I, et al.
J Biol Chem . 2012 Jul; 287(37):31527-39. PMID: 22807449
The natural cytotoxicity receptors are a unique set of activating proteins expressed mainly on the surface of natural killer (NK) cells. The human natural cytotoxicity receptor family comprises the three...
22.
Leng J, Stout-Delgado H, Kavita U, Jacobs A, Tang J, Du W, et al.
Vaccine . 2011 Aug; 29(45):8147-55. PMID: 21854824
Influenza vaccines are less effective in older people than younger people. This impaired ability to protect older people from influenza viral lung infection has important implications as older people suffer...
23.
Powell T, Palath N, DeRome M, Tang J, Jacobs A, Boyd J
Vaccine . 2010 Oct; 29(3):558-69. PMID: 20951665
Nanoparticle vaccines induce potent immune responses in the absence of conventional adjuvant due to the recognition by immune cells of the particle structures, which mimic natural pathogens such as viruses...
24.
Song L, Nakaar V, Kavita U, Price A, Huleatt J, Tang J, et al.
PLoS One . 2008 May; 3(5):e2257. PMID: 18493310
It is known that physical linkage of TLR ligands and vaccine antigens significantly enhances the immunopotency of the linked antigens. We have used this approach to generate novel influenza vaccines...
25.
Huleatt J, Nakaar V, Desai P, Huang Y, Hewitt D, Jacobs A, et al.
Vaccine . 2007 Dec; 26(2):201-14. PMID: 18063235
The recognition of specific pathogen associated molecular patterns (PAMPs) by members of the Toll-like receptor (TLR) family is critical for the activation of the adaptive immune response. Thus, incorporation of...
26.
McDonald W, Huleatt J, Foellmer H, Hewitt D, Tang J, Desai P, et al.
J Infect Dis . 2007 May; 195(11):1607-17. PMID: 17471430
A chimeric protein West Nile virus (WNV) vaccine capable of delivering both innate and adaptive immune signals was designed by fusing a modified version of bacterial flagellin (STF2 Delta )...