Andrea Jacobs
Overview
Explore the profile of Andrea Jacobs including associated specialties, affiliations and a list of published articles.
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26
Citations
2212
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Recent Articles
11.
Irmisch A, Bonilla X, Chevrier S, Lehmann K, Singer F, Toussaint N, et al.
Cancer Cell
. 2021 Jan;
39(3):288-293.
PMID: 33482122
The application and integration of molecular profiling technologies create novel opportunities for personalized medicine. Here, we introduce the Tumor Profiler Study, an observational trial combining a prospective diagnostic approach to...
12.
Tortola L, Jacobs A, Pohlmeier L, Obermair F, Ampenberger F, Bodenmiller B, et al.
Immunity
. 2020 Aug;
53(3):597-613.e6.
PMID: 32735846
CD4 T helper (Th) cells are fundamental players in immunity. Based on the expression of signature cytokines and transcription factors, several Th subsets have been defined. Th cells are thought...
13.
Wagner J, Rapsomaniki M, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, et al.
Cell
. 2019 Apr;
177(5):1330-1345.e18.
PMID: 30982598
Breast cancer is a heterogeneous disease. Tumor cells and associated healthy cells form ecosystems that determine disease progression and response to therapy. To characterize features of breast cancer ecosystems and...
14.
Catena R, Ozcan A, Jacobs A, Chevrier S, Bodenmiller B
Genome Biol
. 2016 Jul;
17(1):142.
PMID: 27356760
Single-cell analysis technologies are essential tools in research and clinical diagnostics. These methods include flow cytometry, mass cytometry, and other microfluidics-based technologies. Most laboratories that employ these methods maintain large...
15.
Bausch-Fluck D, Hofmann A, Bock T, Frei A, Cerciello F, Jacobs A, et al.
PLoS One
. 2015 Apr;
10(3):e0121314.
PMID: 25894527
Cell surface proteins are major targets of biomedical research due to their utility as cellular markers and their extracellular accessibility for pharmacological intervention. However, information about the cell surface protein...
16.
Kopecka J, Campia I, Jacobs A, Frei A, Ghigo D, Wollscheid B, et al.
Oncotarget
. 2015 Feb;
6(9):6776-93.
PMID: 25686827
Multidrug resistance (MDR) in cancer cells is a challenging phenomenon often associated with P-glycoprotein (Pgp) surface expression. Finding new ways to bypass Pgp-mediated MDR still remains a daunting challenge towards...
17.
Giesen C, Wang H, Schapiro D, Zivanovic N, Jacobs A, Hattendorf B, et al.
Nat Methods
. 2014 Mar;
11(4):417-22.
PMID: 24584193
Mass cytometry enables high-dimensional, single-cell analysis of cell type and state. In mass cytometry, rare earth metals are used as reporters on antibodies. Analysis of metal abundances using the mass...
18.
Zivanovic N, Jacobs A, Bodenmiller B
Curr Top Microbiol Immunol
. 2013 Aug;
377:95-109.
PMID: 23918170
Recent advances in inductively coupled plasma mass spectrometry (ICP-MS) as applied in mass cytometry, enabled its broad applicability to life science research. Mass cytometry enables the high-dimensional characterization of cellular...
19.
Powell T, Tang J, DeRome M, Mitchell R, Jacobs A, Deng Y, et al.
Vaccine
. 2013 Mar;
31(15):1898-904.
PMID: 23481177
Epitopes of the circumsporozoite (CS) protein of Plasmodium falciparum, the most pathogenic species of the malaria parasite, have been shown to elicit protective immunity in experimental animals and human volunteers....
20.
Bock T, Moest H, Omasits U, Dolski S, Lundberg E, Frei A, et al.
J Proteome Res
. 2012 Aug;
11(10):4885-93.
PMID: 22909291
Glioblastoma is the most common primary brain tumor in adults with low average survival time after diagnosis. In order to improve glioblastoma treatment, new drug-accessible targets need to be identified....