Andrea Hartwig
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Explore the profile of Andrea Hartwig including associated specialties, affiliations and a list of published articles.
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100
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1770
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Recent Articles
1.
Yan J, Takamiya M, Zhang D, Pace G, Rastegar S, Wang H, et al.
Environ Int
. 2025 Mar;
197:109349.
PMID: 40058302
Zebrafish are widely used not only as a model in ecotoxicology but also to study the potential impact of chemicals on human health. Typically, zebrafish are exposed to chemicals dissolved...
2.
Chromate Affects Gene Expression and DNA Methylation in Long-Term In Vitro Experiments in A549 Cells
Fischer F, Stosser S, Wegmann L, Veh E, Lumpp T, Parsdorfer M, et al.
Int J Mol Sci
. 2024 Sep;
25(18).
PMID: 39337613
Chromate has been shown to dysregulate epigenetic mechanisms such as DNA methylation, leading to changes in gene expression and genomic instability. However, most in vitro studies are limited to short...
3.
Lumpp T, Stosser S, Fischer F, Hartwig A, Koberle B
Int J Mol Sci
. 2024 Jan;
25(2).
PMID: 38256203
The clinical utility of the chemotherapeutic agent cisplatin is restricted by cancer drug resistance, which is either intrinsic to the tumor or acquired during therapy. Epigenetics is increasingly recognized as...
4.
Stosser S, Lumpp T, Fischer F, Gunesch S, Schumacher P, Hartwig A
Int J Mol Sci
. 2023 Oct;
24(20).
PMID: 37894918
Millions of people around the world are exposed to elevated levels of arsenic through food or drinking water. Epidemiological studies have linked chronic arsenic exposure to an increased risk of...
5.
Matthaus T, Stosser S, Seren H, Haberland V, Hartwig A
Int J Mol Sci
. 2023 Sep;
24(18).
PMID: 37762697
BRCA1 is a key player in maintaining genomic integrity with multiple functions in DNA damage response (DDR) mechanisms. Due to its thiol-rich zinc-complexing domain, the protein may also be a...
6.
Dilger M, Armant O, Ramme L, Mulhopt S, Sapcariu S, Schlager C, et al.
Environ Int
. 2023 Sep;
179:108169.
PMID: 37688811
Epidemiological studies identified air pollution as one of the prime causes for human morbidity and mortality, due to harmful effects mainly on the cardiovascular and respiratory systems. Damage to the...
7.
Haberland V, Magin S, Iliakis G, Hartwig A
Int J Mol Sci
. 2023 Jun;
24(12).
PMID: 37373538
Manganese is an essential trace element; nevertheless, on conditions of overload, it becomes toxic, with neurotoxicity being the main concern. Chromate is a well-known human carcinogen. The underlying mechanisms seem...
8.
Hartwig A, van Thriel C
Nanomaterials (Basel)
. 2023 May;
13(9).
PMID: 37177055
The increasing use of nanomaterials in almost every area of our daily life renders toxicological risk assessment a major requirement for their safe handling [...].
9.
Friesen A, Fritsch-Decker S, Mulhopt S, Quarz C, Mahl J, Baumann W, et al.
Int J Mol Sci
. 2023 Feb;
24(3).
PMID: 36768249
In recent years, the use of carbon fibers (CFs) in various sectors of industry has been increasing. Despite the similarity of CF degradation products to other toxicologically relevant materials such...
10.
Caipa Garcia A, Kucab J, Al-Serori H, Beck R, Fischer F, Hufnagel M, et al.
Int J Mol Sci
. 2023 Jan;
24(1).
PMID: 36614051
Organoids are 3D cultures that to some extent reproduce the structure, composition and function of the mammalian tissues from which they derive, thereby creating in vitro systems with more in...