Matthias Hufnagel
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Explore the profile of Matthias Hufnagel including associated specialties, affiliations and a list of published articles.
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11
Citations
141
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Recent Articles
1.
Hufnagel M, Rademaekers A, Weisert A, Haberlein H, Franken S
Front Pharmacol
. 2024 Sep;
15:1371613.
PMID: 39239645
Dicaffeoylquinic acids (DCQAs) are polyphenolic compounds found in various medicinal plants such as and whose multi-constituent extracts are used worldwide to treat respiratory diseases. Besides triterpenes, saponins, alkamides, and other...
2.
Friesen A, Fritsch-Decker S, Mulhopt S, Quarz C, Mahl J, Baumann W, et al.
Int J Mol Sci
. 2023 Feb;
24(3).
PMID: 36768249
In recent years, the use of carbon fibers (CFs) in various sectors of industry has been increasing. Despite the similarity of CF degradation products to other toxicologically relevant materials such...
3.
Caipa Garcia A, Kucab J, Al-Serori H, Beck R, Fischer F, Hufnagel M, et al.
Int J Mol Sci
. 2023 Jan;
24(1).
PMID: 36614051
Organoids are 3D cultures that to some extent reproduce the structure, composition and function of the mammalian tissues from which they derive, thereby creating in vitro systems with more in...
4.
Friesen A, Fritsch-Decker S, Hufnagel M, Mulhopt S, Stapf D, Weiss C, et al.
Int J Mol Sci
. 2022 Jul;
23(14).
PMID: 35887123
In vitro lung cell models like air-liquid interface (ALI) and 3D cell cultures have advanced greatly in recent years, being especially valuable for testing advanced materials (e.g., nanomaterials, fibrous substances)...
5.
Friesen A, Fritsch-Decker S, Hufnagel M, Mulhopt S, Stapf D, Hartwig A, et al.
Int J Mol Sci
. 2022 Jun;
23(12).
PMID: 35742856
The occupational exposure to particles such as crystalline quartz and its impact on the respiratory tract have been studied extensively in recent years. For hazard assessment, the development of physiologically...
6.
Wall J, Ag Seleci D, Schworm F, Neuberger R, Link M, Hufnagel M, et al.
Nanomaterials (Basel)
. 2022 Jan;
12(1).
PMID: 35010097
While the toxicity of metal-based nanoparticles (NP) has been investigated in an increasing number of studies, little is known about metal-based fibrous materials, so-called nanowires (NWs). Within the present study,...
7.
Hufnagel M, May N, Wall J, Wingert N, Garcia-Kaufer M, Arif A, et al.
Nanomaterials (Basel)
. 2021 Jul;
11(7).
PMID: 34199005
The use of nanomaterials incorporated into plastic products is increasing steadily. By using nano-scaled filling materials, thermoplastics, such as polyethylene (PE), take advantage of the unique properties of nanomaterials (NM)....
8.
Hufnagel M, Neuberger R, Wall J, Link M, Friesen A, Hartwig A
Int J Mol Sci
. 2021 Jun;
22(9).
PMID: 34068728
To mimic more realistic lung tissue conditions, co-cultures of epithelial and immune cells are one comparatively easy-to-use option. To reveal the impact of immune cells on the mode of action...
9.
Aberle L, Kruger A, Reber J, Lippmann M, Hufnagel M, Schmalz M, et al.
Nucleic Acids Res
. 2020 Jul;
48(18):10015-10033.
PMID: 32667640
Poly(ADP-ribosyl)ation regulates numerous cellular processes like genome maintenance and cell death, thus providing protective functions but also contributing to several pathological conditions. Poly(ADP-ribose) (PAR) molecules exhibit a remarkable heterogeneity in...
10.
Hufnagel M, Schoch S, Wall J, Strauch B, Hartwig A
Chem Res Toxicol
. 2020 Apr;
33(5):1237-1249.
PMID: 32285662
To assess the toxicity of nanomaterials, most studies have been performed under submerged conditions, which do not reflect physiological conditions upon inhalation. An air-liquid interface (ALI) exposure may provide more...