Andrea Gonzalez-Morales
Overview
Explore the profile of Andrea Gonzalez-Morales including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
138
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Recent Articles
1.
Lachen-Montes M, Gonzalez-Morales A, Fernandez-Irigoyen J, Santamaria E
Methods Mol Biol
. 2019 Aug;
2044:273-289.
PMID: 31432419
Nowadays, diagnosis of neurodegenerative disorders is mainly based on neuroimaging and clinical symptoms, although postmortem neuropathological confirmation remains the gold standard diagnostic technique. Therefore, cerebrospinal fluid (CSF) proteome is considered...
2.
Gonzalez-Morales A, Lachen-Montes M, Fernandez-Irigoyen J, Santamaria E
Methods Mol Biol
. 2019 Aug;
2044:233-246.
PMID: 31432416
The brain is the most complex organ of the human body, and the study of the different diseases and injuries that affect it is far behind the ones that affect...
3.
Lachen-Montes M, Gonzalez-Morales A, Fernandez-Irigoyen J, Santamaria E
Methods Mol Biol
. 2019 Aug;
2044:155-168.
PMID: 31432412
Cerebrospinal fluid (CSF) is in direct contact with the brain and represents a valuable source of mediators that reflect metabolic processes occurring in the central nervous system (CNS). In this...
4.
Lachen-Montes M, Gonzalez-Morales A, Palomino M, Ausin K, Gomez-Ochoa M, Zelaya M, et al.
Front Aging Neurosci
. 2019 Jun;
11:141.
PMID: 31244650
The olfactory bulb (OB) is the first processing station in the olfactory pathway. Despite smell impairment, which is considered an early event in Alzheimer's disease (AD), little is known about...
5.
Lachen-Montes M, Gonzalez-Morales A, Schvartz D, Zelaya M, Ausin K, Fernandez-Irigoyen J, et al.
J Proteomics
. 2019 Apr;
201:37-47.
PMID: 30999060
Mild olfactory dysfunction has been observed in frontotemporal dementias (FTD). However, the underlying molecular mechanisms associated to this deficit are poorly understood. We applied quantitative proteomics to analyze pathological effects...
6.
Oncolytic adenovirus Delta-24-RGD induces a widespread glioma proteotype remodeling during autophagy
Gonzalez-Morales A, Zabaleta A, Garcia-Moure M, Alonso M, Fernandez-Irigoyen J, Santamaria E
J Proteomics
. 2018 Dec;
194:168-178.
PMID: 30503830
Adenovirus Delta-24-RGD has shown a remarkable efficacy in a phase I clinical trial for glioblastoma. Delta-24-RGD induces autophagy in glioma cells, however, the molecular derangements associated with Delta-24-RGD infection remains...
7.
Lachen-Montes M, Gonzalez-Morales A, Iloro I, Elortza F, Ferrer I, Gveric D, et al.
Neurobiol Aging
. 2018 Oct;
73:123-134.
PMID: 30342273
Olfactory dysfunction is one of the earliest features in Lewy-type alpha-synucleinopathies (LTSs) such as Parkinson's disease (PD). However, the underlying molecular mechanisms associated to smell impairment are poorly understood. Applying...
8.
Gonzalez-Morales A, Zabaleta A, Guruceaga E, Alonso M, Garcia-Moure M, Fernandez-Irigoyen J, et al.
Oncotarget
. 2018 Aug;
9(57):31045-31065.
PMID: 30123426
Glioblastoma multiforme (GBM) is the most common and aggressive type of malignant glioma. Oncolytic adenoviruses are being modified to exploit the aberrant expression of proteins in tumor cells to increase...
9.
Palomino-Alonso M, Lachen-Montes M, Gonzalez-Morales A, Ausin K, Perez-Mediavilla A, Fernandez-Irigoyen J, et al.
Int J Mol Sci
. 2017 Oct;
18(11).
PMID: 29077059
Olfaction is often deregulated in Alzheimer's disease (AD) patients, and is also impaired in transgenic Tg2576 AD mice, which overexpress the Swedish mutated form of human amyloid precursor protein (APP)....
10.
Lachen-Montes M, Gonzalez-Morales A, Zelaya M, Perez-Valderrama E, Ausin K, Ferrer I, et al.
Sci Rep
. 2017 Aug;
7(1):9115.
PMID: 28831118
Olfactory dysfunction is among the earliest features of Alzheimer's disease (AD). Although neuropathological abnormalities have been detected in the olfactory bulb (OB), little is known about its dynamic biology. Here,...