Andrea Felser
Overview
Explore the profile of Andrea Felser including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
504
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Recent Articles
1.
Mathis D, du Toit T, Altinkilic E, Stojkov D, Urzi C, Voegel C, et al.
J Steroid Biochem Mol Biol
. 2024 Jun;
243:106561.
PMID: 38866189
The role of mitochondria in steroidogenesis is well established. However, the specific effects of mitochondrial dysfunction on androgen synthesis are not fully understood. In this study, we investigate the effects...
2.
Bertschi N, Steck O, Luther F, Bazzini C, von Meyenn L, Scharli S, et al.
Nat Commun
. 2023 Apr;
14(1):2471.
PMID: 37120582
T helper 9 (T9) cells promote allergic tissue inflammation and express the type 2 cytokines, IL-9 and IL-13, as well as the transcription factor, PPAR-γ. However, the functional role of...
3.
Felser A, Agyeman P, Horn M, Stranzinger E, Kopp M, Moser B
Klin Padiatr
. 2023 Feb;
235(4):243-244.
PMID: 36848942
No abstract available.
4.
Melin N, Yarahmadov T, Sanchez-Taltavull D, Birrer F, Brodie T, Petit B, et al.
JHEP Rep
. 2022 Jun;
4(7):100508.
PMID: 35712694
Background & Aims: High-dose irradiation is an essential tool to help control the growth of hepatic tumors, but it can cause radiation-induced liver disease (RILD). This life-threatening complication manifests itself...
5.
Metabolic resistance to the inhibition of mitochondrial transcription revealed by CRISPR-Cas9 screen
Mennuni M, Filograna R, Felser A, Bonekamp N, Giavalisco P, Lytovchenko O, et al.
EMBO Rep
. 2021 Nov;
23(1):e53054.
PMID: 34779571
Cancer cells depend on mitochondria to sustain their increased metabolic need and mitochondria therefore constitute possible targets for cancer treatment. We recently developed small-molecule inhibitors of mitochondrial transcription (IMTs) that...
6.
Hertig D, Maddah S, Memedovski R, Kurth S, Moreno A, Pennestri M, et al.
Analyst
. 2021 Jun;
146(13):4326-4339.
PMID: 34106111
Background: Because of the interplay between mitochondrial respiration and cellular metabolism, the simultaneous monitoring of both cellular processes provides important insights for the understanding of biological processes. NMR flow systems...
7.
Bonekamp N, Peter B, Hillen H, Felser A, Bergbrede T, Choidas A, et al.
Nature
. 2020 Dec;
588(7839):712-716.
PMID: 33328633
Altered expression of mitochondrial DNA (mtDNA) occurs in ageing and a range of human pathologies (for example, inborn errors of metabolism, neurodegeneration and cancer). Here we describe first-in-class specific inhibitors...
8.
Guarino M, Kumar P, Felser A, Terracciano L, Guixe-Muntet S, Humar B, et al.
Cancers (Basel)
. 2020 Jun;
12(6).
PMID: 32486073
Non-alcoholic fatty liver disease (NAFLD) leads to steatohepatitis (NASH), fibrosis, and hepatocellular carcinoma. For sedentary patients, lifestyle interventions combining exercise and dietary changes are a cornerstone of treatment. However, the...
9.
Liu H, He Z, Germic N, Ademi H, Frangez Z, Felser A, et al.
Cell Death Differ
. 2019 Dec;
27(6):1965-1980.
PMID: 31844253
In contrast to the "Warburg effect" or aerobic glycolysis earlier generalized as a phenomenon in cancer cells, more and more recent evidence indicates that functional mitochondria are pivotal for ensuring...
10.
Bittner A, Ducray A, Stoffel M, Felser A, Mevissen M
Toxicol Appl Pharmacol
. 2019 Nov;
385:114800.
PMID: 31678605
Laser tissue soldering is a novel treatment method for injuries of hollow organs such as cerebrovascular aneurysms. Nanomaterials contained in the solder are foreign to the body. Hence, it is...