Andrea Emanuelli
Overview
Explore the profile of Andrea Emanuelli including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
103
Followers
0
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Recent Articles
1.
Chouleur T, Emanuelli A, Souleyreau W, Derieppe M, Leboucq T, Hardy S, et al.
Cancer Res Commun
. 2024 Jun;
4(7):1702-1714.
PMID: 38904264
Significance: High levels of PTP4A2 are associated with poor outcomes in patients with glioma and in mouse models. PTP4A2 depletion increases apoptosis and proinflammatory signals in GBM xenograft models, significantly...
2.
Alvarez-Arenas A, Souleyreau W, Emanuelli A, Cooley L, Bernhard J, Bikfalvi A, et al.
PLoS Comput Biol
. 2022 Aug;
18(8):e1010444.
PMID: 36007057
Distant metastasis-free survival (DMFS) curves are widely used in oncology. They are classically analyzed using the Kaplan-Meier estimator or agnostic statistical models from survival analysis. Here we report on a...
3.
Shah P, Boutros-Suleiman S, Emanuelli A, Paolini B, Levy-Cohen G, Blank M
Cancers (Basel)
. 2022 Apr;
14(7).
PMID: 35406379
KAP1 is an essential nuclear factor acting as a scaffold for protein complexes repressing transcription. KAP1 plays fundamental role in normal and cancer cell biology, affecting cell proliferation, DNA damage...
4.
Koganti P, Kadali V, Manikoth Ayyathan D, Emanuelli A, Paolini B, Levy-Cohen G, et al.
Cell Mol Life Sci
. 2022 Apr;
79(5):237.
PMID: 35403872
Epitranscriptomic changes in RNA catalyzed by the RNA-editing enzyme ADAR1 play an essential role in the regulation of diverse molecular and cellular processes, both under physiological conditions and in disease...
5.
Cooley L, Rudewicz J, Souleyreau W, Emanuelli A, Alvarez-Arenas A, Clarke K, et al.
Mol Cancer
. 2021 Oct;
20(1):136.
PMID: 34670568
Background: Renal Cell Carcinoma (RCC) is difficult to treat with 5-year survival rate of 10% in metastatic patients. Main reasons of therapy failure are lack of validated biomarkers and scarce...
6.
Ilic N, Tao Y, Boutros-Suleiman S, Kadali V, Emanuelli A, Levy-Cohen G, et al.
FASEB J
. 2021 Mar;
35(4):e21436.
PMID: 33734501
Poly(ADP-ribose) polymerase 1 (PARP1) is a key molecular stress sensor and response mediator implicated in multiple cellular functions in health and diseases. Despite its importance and intrinsic involvement in pivotal...
7.
Manikoth Ayyathan D, Koganti P, Marcu-Malina V, Litmanovitch T, Trakhtenbrot L, Emanuelli A, et al.
Oncogene
. 2020 Feb;
39(16):3396-3410.
PMID: 32103168
E3 ubiquitin ligases (E3s) play essential roles in the maintenance of tissue homeostasis under normal and stress conditions, as well as in disease states, particularly in cancer. However, the role...
8.
Emanuelli A, Manikoth Ayyathan D, Koganti P, Shah P, Apel-Sarid L, Paolini B, et al.
Cancers (Basel)
. 2019 Apr;
11(4).
PMID: 31003445
SMURF2, an E3 ubiquitin ligase and suggested tumor suppressor, operates in normal cells to prevent genomic instability and carcinogenesis. However, the mechanisms underlying SMURF2 inactivation in human malignancies remain elusive,...
9.
Borroni A, Emanuelli A, Shah P, Ilic N, Apel-Sarid L, Paolini B, et al.
Aging Cell
. 2018 Feb;
17(2).
PMID: 29405587
A-lamins, encoded by the LMNA gene, are major structural components of the nuclear lamina coordinating essential cellular processes. Mutations in the LMNA gene and/or alterations in its expression levels have...
10.
Emanuelli A, Borroni A, Apel-Sarid L, Shah P, Manikoth Ayyathan D, Koganti P, et al.
Cancer Res
. 2017 Jun;
77(16):4217-4227.
PMID: 28611047
DNA topoisomerase IIα (Topo IIα) ensures genomic integrity and unaltered chromosome inheritance and serves as a major target of several anticancer drugs. Topo IIα function is well understood, but how...