Andrea E Doak
Overview
Explore the profile of Andrea E Doak including associated specialties, affiliations and a list of published articles.
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5
Citations
78
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Recent Articles
1.
Yamamoto A, Huang Y, Krajina B, McBirney M, Doak A, Qu S, et al.
Proc Natl Acad Sci U S A
. 2023 Feb;
120(10):e2214888120.
PMID: 36853945
Necrosis in the tumor interior is a common feature of aggressive cancers that is associated with poor clinical prognosis and the development of metastasis. How the necrotic core promotes metastasis...
2.
Yamamoto A, Doak A, Cheung K
Annu Rev Pathol
. 2022 Oct;
18:231-256.
PMID: 36207009
Metastatic dissemination has lethal consequences for cancer patients. Accruing evidence supports the hypothesis that tumor cells can migrate and metastasize as clusters of cells while maintaining contacts with one another....
3.
Schubert L, Le A, Estrada-Bernal A, Doak A, Yoo M, Ferrara S, et al.
Mol Pharmacol
. 2021 Apr;
99(6):435-447.
PMID: 33795352
Rearranged during transfection () rearrangements occur in 1% to 2% of lung adenocarcinomas as well as other malignancies and are now established targets for tyrosine kinase inhibitors. We developed three...
4.
Estrada-Bernal A, Le A, Doak A, Tirunagaru V, Silva S, Bull M, et al.
Clin Cancer Res
. 2020 Dec;
27(5):1463-1475.
PMID: 33355298
Purpose: Approved therapies for exon 20, mutations, and fusions are currently lacking for non-small cell lung cancer and other cancers. Tarloxotinib is a prodrug that harnesses tumor hypoxia to generate...
5.
Marcus J, Burke R, Doak A, Park S, Orth J
Cell Cycle
. 2018 Jul;
17(11):1329-1344.
PMID: 30037299
The tumor suppressor protein p53 is central to the cellular stress response and may be a predictive biomarker for cancer treatments. Upon stress, wildtype p53 accumulates in the nucleus where...